Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | CPT2 | P23786 | 1/20 | 0.37 |
| ▸ | CPT1A | P50416 | 1/20 | 0.37 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.37 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.36 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9056444 | 1.00 | HPGDS (0.41) | HPGDSACHENPC1RAB9AALDH1A1 | |
| Hydrochloric Acid SCHEMBL9057145 | 0.99 | HPGDS (0.40) | HPGDSACHENPC1RAB9AALDH1A1 | |
| SCHEMBL9053271 | 0.86 | HTR2C (0.38) | HPGDSNPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL9053281 | 0.86 | HTR2C (0.38) | HPGDSNPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL9055358 | 0.86 | HPGDS (0.36) | HPGDSACHEDGAT1FFAR4BAZ2A | |
| SCHEMBL9055350 | 0.86 | HPGDS (0.36) | HPGDSACHEDGAT1FFAR4BAZ2A | |
| SCHEMBL9057060 | 0.83 | BAZ2A (0.36) | HPGDSACHEDGAT1FFAR4BAZ2A | |
| SCHEMBL9054080 | 0.83 | BAZ2A (0.39) | HPGDSACHEDGAT1FFAR4BAZ2A | |
| SCHEMBL9057063 | 0.83 | BAZ2A (0.36) | HPGDSACHEDGAT1FFAR4BAZ2A | |
| SCHEMBL9054357 | 0.83 | FFAR4 (0.36) | HPGDSACHEDGAT1FFAR4BAZ2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996004271-A1 | CONDENSED AZEPINE DERIVATIVES, DRUGS CONTAINING THESE COMPOUNDS AND METHODS FOR PREPARING THEM | DR. KARL THOMAE GMBH (DE) | 1996-02-15 | — | — | WO | claimed |