Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 3/20 | 0.69 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.62 |
| ▸ | ADRA1D | P25100 | 6/20 | 0.59 |
| ▸ | ADRA1A | P35348 | 6/20 | 0.59 |
| ▸ | ADRA1B | P35368 | 5/20 | 0.59 |
| ▸ | DRD3 | P35462 | 1/20 | 0.58 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8188739 | 0.92 | OPRM1 (0.57) | DRD2OPRM1ADRA1DADRA1AADRA1B | |
| SCHEMBL9053325 | 0.92 | DRD2 (0.72) | DRD2OPRM1ADRA1ADRD3 | |
| SCHEMBL2112765 | 0.83 | OPRM1 (0.61) | OPRM1ADRA1DADRA1AADRA1BOPRD1 | |
| SCHEMBL11742946 | 0.83 | DRD2 (0.78) | DRD2ADRA1DADRA1AADRA1BDRD3 | |
| Hydrochloric Acid SCHEMBL11746185 | 0.82 | DRD2 (0.76) | DRD2ADRA1DADRA1AADRA1BDRD3 | |
| SCHEMBL8986029 | 0.82 | DRD2 (1.00) | DRD2OPRM1ADRA1DADRA1AADRA1B | |
| SCHEMBL9052123 | 0.81 | DRD2 (0.74) | DRD2ADRA1DADRA1AADRA1BDRD3 | |
| SCHEMBL6198369 | 0.79 | OPRM1 (0.71) | OPRM1ADRA1DADRA1AADRA1BOPRD1 | |
| SCHEMBL27796310 | 0.79 | OPRM1 (0.71) | OPRM1ADRA1DADRA1AADRA1BOPRD1 | |
| SCHEMBL918200 | 0.79 | OPRM1 (0.63) | OPRM1ADRA1DADRA1AADRA1BOPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996002250-A1 | HALOPERIDOL ANALOGS AND THE USE THEREOF | ACEA PHARMACEUTICALS INC. (US) | 1996-02-01 | — | — | WO | disclosed |