Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 8/20 | 0.54 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.41 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9048486 | 0.87 | PTGIR (0.55) | PTGIRSIGMAR1TBXAS1 | |
| SCHEMBL8858400 | 0.84 | PTGIR (0.75) | PTGIRSIGMAR1TBXAS1 | |
| SCHEMBL9050863 | 0.81 | PTGIR (0.50) | PTGIRSIGMAR1 | |
| SCHEMBL9050857 | 0.79 | PTGIR (0.43) | PTGIRSIGMAR1 | |
| SCHEMBL9048482 | 0.78 | PTGIR (0.48) | PTGIRSIGMAR1 | |
| SCHEMBL9048090 | 0.78 | PTGIR (0.69) | PTGIRSIGMAR1TBXAS1 | |
| SCHEMBL9050353 | 0.77 | ACHE (0.43) | PTGIR | |
| SCHEMBL9047812 | 0.77 | PTGIR (0.65) | PTGIRTBXAS1 | |
| SCHEMBL8858598 | 0.77 | PTGIR (0.65) | PTGIRSIGMAR1TBXAS1 | |
| SCHEMBL8858404 | 0.76 | PTGIR (0.72) | PTGIRTBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0542203-B1 | Fused benzeneoxyacetic acid derivatives as PGl2 receptor agonists | ONO PHARMACEUTICAL CO (JP) | 1996-07-03 | — | — | EP | disclosed |
| US-5344836-A | Fused benzeneoxyacetic acid derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1994-09-06 | — | — | US | disclosed |