Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 8/20 | 0.43 |
| ▸ | PTGIR | P43119 | 5/20 | 0.41 |
| ▸ | MAOA | P21397 | 3/20 | 0.39 |
| ▸ | MAOB | P27338 | 3/20 | 0.39 |
| ▸ | BCHE | P06276 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9050863 | 0.86 | PTGIR (0.50) | PTGIR | |
| SCHEMBL9050857 | 0.85 | PTGIR (0.43) | ACHEPTGIR | |
| SCHEMBL8811047 | 0.84 | ACHE (0.45) | ACHEPTGIRMAOAMAOBBCHE | |
| SCHEMBL9050358 | 0.84 | PTGIR (0.43) | ACHEPTGIRMAOAMAOB | |
| SCHEMBL8414338 | 0.82 | ACHE (0.46) | ACHEPTGIRMAOAMAOBBCHE | |
| SCHEMBL8858535 | 0.79 | ACHE (0.45) | ACHEMAOAMAOBBCHE | |
| SCHEMBL8858484 | 0.78 | PTGIR (0.61) | PTGIR | |
| SCHEMBL8808959 | 0.78 | PTGIR (0.47) | PTGIR | |
| SCHEMBL9050297 | 0.78 | CHRM2 (0.46) | PTGIR | |
| SCHEMBL9053439 | 0.77 | PTGIR (0.54) | PTGIR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0542203-B1 | Fused benzeneoxyacetic acid derivatives as PGl2 receptor agonists | ONO PHARMACEUTICAL CO (JP) | 1996-07-03 | — | — | EP | disclosed |
| US-5344836-A | Fused benzeneoxyacetic acid derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1994-09-06 | — | — | US | disclosed |