Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8577595 | 0.83 | ALDH1A1 (0.46) | ALDH1A1GAAKDM4EHSD17B10NPC1 | |
| SCHEMBL13292304 | 0.78 | ALDH1A1 (0.44) | ALDH1A1GAAKDM4EHSD17B10POLB | |
| SCHEMBL2631833 | 0.75 | ALDH1A1 (0.48) | ALDH1A1GAAKDM4EHSD17B10POLB | |
| SCHEMBL11213802 | 0.75 | ALDH1A1 (0.52) | ALDH1A1GAAKDM4EHSD17B10NPC1 | |
| SCHEMBL29441612 | 0.75 | ALDH1A1 (0.52) | ALDH1A1GAAKDM4EHSD17B10NPC1 | |
| SCHEMBL17398693 | 0.74 | CYP19A1 (0.35) | ALDH1A1POLB | |
| SCHEMBL13989109 | 0.73 | ALDH1A1 (0.41) | ALDH1A1KDM4EHSD17B10PDE4DPOLB | |
| SCHEMBL17427515 | 0.73 | ALDH1A1 (0.40) | ALDH1A1GAAKDM4EHSD17B10POLB | |
| SCHEMBL14331973 | 0.73 | LMNA (0.41) | ALDH1A1KDM4EHSD17B10LMNAMAPT | |
| SCHEMBL9910017 | 0.73 | ALDH1A1 (0.46) | ALDH1A1GAAKDM4EHSD17B10POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996003124-A1 | DYNEMICIN ANALOGS | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 1996-02-08 | — | — | WO | disclosed |