Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 2/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.36 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.35 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.35 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.35 |
| ▸ | TMPRSS6 | Q8IU80 | 1/20 | 0.35 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18906060 | 0.78 | KDM4E (0.44) | F2PRSS1PRSS2PRSS3TMPRSS6 | |
| SCHEMBL252810 | 0.73 | — | — | |
| SCHEMBL8680424 | 0.73 | GABRA1 (0.45) | HTR1AADRA2CADRA2AADRA2BNISCH | |
| SCHEMBL939841 | 0.73 | GABRA1 (0.45) | HTR1AADRA2CADRA2AADRA2BNISCH | |
| SCHEMBL29763626 | 0.72 | GABRA1 (0.56) | HTR1AADRA2CADRA2AADRA2BNISCH | |
| SCHEMBL173300 | 0.72 | GABRA1 (0.56) | HTR1AADRA2CADRA2AADRA2BNISCH | |
| SCHEMBL29002822 | 0.70 | KDM4E (0.42) | ALDH1A1KDM4ETP53 | |
| SCHEMBL6101472 | 0.70 | F2 (0.51) | GABRA1GABRB2F2PRSS1PRSS2 | |
| SCHEMBL19437729 | 0.70 | GABRA1 (0.54) | HTR1AADRA2CADRA2AADRA2BNISCH | |
| Phosphine SCHEMBL28908229 | 0.70 | GABRA1 (0.54) | HTR1AADRA2CADRA2AADRA2BNISCH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0459406-B1 | Mesomorphic compound, liquid crystal composition, liquid crystal device, display apparatus and display method | CANON KK (JP) | 1996-01-31 | — | — | EP | disclosed |