Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 4/20 | 0.40 |
| ▸ | NR1H3 | Q13133 | 4/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.34 |
| ▸ | AR | P10275 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL631933 | 0.73 | TAAR1 (0.46) | NR1H2NR1H3TSHRMAPTNPSR1 | |
| SCHEMBL632702 | 0.72 | CNR2 (0.48) | NR1H2NR1H3NPC1TSHRRAB9A | |
| SCHEMBL5891787 | 0.70 | FNTA (0.38) | — | |
| SCHEMBL5891767 | 0.70 | LIMK1 (0.42) | ALDH1A1 | |
| Hydrochloric Acid SCHEMBL8368374 | 0.69 | FNTA (0.38) | — | |
| Hydrochloric Acid SCHEMBL8368491 | 0.69 | LIMK1 (0.42) | ALDH1A1 | |
| SCHEMBL10188359 | 0.68 | CNR2 (0.45) | NR1H2NR1H3LMNATP53MAPT | |
| SCHEMBL633148 | 0.68 | NOX1 (0.52) | NPC1TSHRRAB9ALMNATP53 | |
| SCHEMBL633000 | 0.68 | GRIN2A (0.43) | NR1H2NR1H3MAPTALDH1A1HTT | |
| SCHEMBL632294 | 0.68 | TRPM5 (0.50) | NR1H2NR1H3NPC1TSHRRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996037204-A1 | INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | MERCK & CO., INC. (US) | 1996-11-28 | — | — | WO | disclosed |