SCHEMBL632294

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL633000	0.85	GRIN2A (0.43)	ALDH1A1MAPK1KDM4EMAPTNR1H2
	SCHEMBL632206	0.82	ALDH1A1 (0.40)	ALDH1A1MAPK1SMN1; SMN2TAAR1MAPT
	SCHEMBL632399	0.82	GRIN1 (0.36)	TRPM5TAAR1NR1H2NR1H3GRIN1
	SCHEMBL632151	0.82	GRIN1 (0.36)	TRPM5NR1H2NR1H3GRIN1GRIN2A
	SCHEMBL633166	0.81	TRPM5 (0.34)	TRPM5GBA1SMN1; SMN2TAAR1LMNA
	SCHEMBL631933	0.81	TAAR1 (0.46)	TAAR1MAPTNR1H2NR1H3GRIN1
	SCHEMBL632702	0.80	CNR2 (0.48)	ALDH1A1KDM4ENPC1TAAR1MEN1
	SCHEMBL631935	0.79	S1PR1 (0.47)	ALDH1A1MAPK1MEN1MAPTKMT2A
	SCHEMBL633125	0.79	CNR2 (0.42)	TRPM5
	SCHEMBL631671	0.79	NR1H2 (0.42)	ALDH1A1TAAR1NR1H2NR1H3LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.