SCHEMBL9054071

SCHEMBL9054071

Cc1cc(C)c(-c2c(Br)n(S(C)(=O)=O)c3c(NCCCCC4CC4)ncnc23)c(C)c1

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CDK1 P06493 1/20 0.31
HRH4 Q9H3N8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9055343 0.86 HRH4 (0.34) CDK1HRH4
SCHEMBL7220802 0.60 MAPK1 (0.35) HRH4
SCHEMBL7561611 0.59 CRHR1 (0.46)
SCHEMBL7216049 0.57 MAPK1 (0.35) HRH4
SCHEMBL11844026 0.55 ENPP1 (0.56)
SCHEMBL11852799 0.55 ENPP1 (0.56)
SCHEMBL11861006 0.55 ENPP1 (0.56)
SCHEMBL25656055 0.52 ENPP1 (0.58)
SCHEMBL20208501 0.51 HCAR2 (0.35)
SCHEMBL25656053 0.50 ENPP1 (0.54)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1996035689-A1 NOVEL DEAZAPURINE DERIVATIVES; A NEW CLASS OF CRF1 SPECIFIC LIGANDS NEUROGEN CORPORATION (US) 1996-11-14 WO disclosed