Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 3/20 | 0.65 |
| ▸ | MAOB | P27338 | 2/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | MAOA | P21397 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | LAP3 | P28838 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.53 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.53 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.53 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.53 |
| ▸ | BCHE | P06276 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9054687 | 0.98 | LTA4H (0.63) | LTA4HMAOBCYP1A2CYP2C19CYP2D6 | |
| SCHEMBL8866173 | 0.98 | LTA4H (0.62) | LTA4HMAOBCYP1A2CYP2C19CYP2D6 | |
| Hydrochloric Acid SCHEMBL8865569 | 0.97 | LTA4H (0.60) | LTA4HMAOBCYP1A2CYP2C19CYP2D6 | |
| SCHEMBL8866250 | 0.97 | LTA4H (0.65) | LTA4HMAOBCYP1A2CYP2C19CYP2D6 | |
| Hydrochloric Acid SCHEMBL8866048 | 0.95 | LTA4H (0.63) | LTA4HMAOBCYP1A2CYP2C19CYP2D6 | |
| SCHEMBL7036801 | 0.93 | LTA4H (0.57) | LTA4HMAOBCYP1A2CYP2C19CYP2D6 | |
| SCHEMBL6568552 | 0.83 | LMNA (0.58) | LTA4HMAOBCYP1A2CYP2C19GAA | |
| SCHEMBL7766511 | 0.83 | MAOB (0.56) | LTA4HMAOBCYP1A2CYP2C19GAA | |
| SCHEMBL322827 | 0.83 | LMNA (0.58) | LTA4HMAOBCYP1A2CYP2C19GAA | |
| SCHEMBL8862833 | 0.82 | GRIN2D (0.68) | LTA4HMAOBCYP1A2CYP2C19GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0356035-B1 | Arylkalkyl-amines and -amides having anticonvulsant and neuroprotective properties | ASTRA AB (SE) | 1996-03-13 | — | — | EP | disclosed |