Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.44 |
| ▸ | TMEM97 | Q5BJF2 | 4/20 | 0.44 |
| ▸ | CTSB | P07858 | 1/20 | 0.42 |
| ▸ | CTSS | P25774 | 1/20 | 0.42 |
| ▸ | CTSK | P43235 | 1/20 | 0.42 |
| ▸ | FKBP1A | P62942 | 4/20 | 0.42 |
| ▸ | PREP | P48147 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7049415 | 0.85 | SMN1; SMN2 (0.50) | FKBP1AL3MBTL1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL9047694 | 0.74 | PREP (0.50) | SIGMAR1TMEM97CTSBCTSSCTSK | |
| SCHEMBL2859914 | 0.73 | SMN1; SMN2 (0.53) | FKBP1AL3MBTL1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL2860475 | 0.73 | SMN1; SMN2 (0.50) | FKBP1ATSHRL3MBTL1LMNANPC1 | |
| SCHEMBL1190089 | 0.73 | PREP (0.58) | CTSBCTSSCTSKFKBP1APREP | |
| SCHEMBL27848134 | 0.73 | PREP (0.58) | CTSBCTSSCTSKFKBP1APREP | |
| SCHEMBL25678350 | 0.73 | PREP (0.58) | CTSBCTSSCTSKFKBP1APREP | |
| SCHEMBL3534026 | 0.73 | SMN1; SMN2 (0.55) | FKBP1ANPC1RAB9ASMN1; SMN2POLB | |
| SCHEMBL30722459 | 0.72 | SIGMAR1 (0.51) | SIGMAR1TMEM97FKBP1APREPNPC1 | |
| SCHEMBL2861163 | 0.71 | SMN1; SMN2 (0.57) | FKBP1ANPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0714392-A1 | HETEROCYCLES USEFUL AS NEUROKININ ANTAGONISTS | ZENECA LIMITED (GB) | 1996-06-05 | — | — | EP | disclosed |