Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CCR5 | P51681 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7844397 | 0.88 | HTT (0.44) | HTTPKMSMN1; SMN2LMNA | |
| SCHEMBL7847850 | 0.85 | HTT (0.46) | HTT | |
| Hydrochloric Acid SCHEMBL7848836 | 0.84 | HTT (0.45) | HTT | |
| SCHEMBL7847305 | 0.84 | HTT (0.46) | HTTPKMSMN1; SMN2CYP2D6CCR5 | |
| SCHEMBL7835077 | 0.82 | HTT (0.43) | HTTSMN1; SMN2LMNA | |
| SCHEMBL7842644 | 0.78 | CNR2 (0.37) | — | |
| SCHEMBL7844596 | 0.77 | HTT (0.48) | HTTSMN1; SMN2CYP2D6CCR5LMNA | |
| SCHEMBL7842338 | 0.75 | — | — | |
| SCHEMBL7849083 | 0.74 | PTGER4 (0.40) | — | |
| SCHEMBL8564247 | 0.74 | ASAH1 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996033196-A1 | INDOLE-3-CARBONYL AND INDOLE-3-SULFONYL DERIVATIVES AS PLATELET ACTIVATING FACTOR ANTAGONISTS | ABBOTT LABORATORIES (US) | 1996-10-24 | — | — | WO | claimed |