Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ASAH1 | Q13510 | 3/20 | 0.39 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.34 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.34 |
| ▸ | RARA | P10276 | 1/20 | 0.33 |
| ▸ | RARB | P10826 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7845141 | 0.82 | HDAC2 (0.39) | SERPINE1GRIN2B | |
| SCHEMBL9054223 | 0.74 | HTT (0.42) | — | |
| SCHEMBL28743917 | 0.70 | BCHE (0.45) | BCHEALDH1A1KMT2ATP53MAPT | |
| SCHEMBL8564251 | 0.69 | GPR17 (0.42) | GSK3BALDH1A1KMT2A | |
| SCHEMBL30622564 | 0.66 | NPC1 (0.39) | BCHEALDH1A1KMT2A | |
| SCHEMBL30182164 | 0.65 | KMT2A (0.36) | ASAH1BCHEALDH1A1KMT2ATP53 | |
| SCHEMBL1553715 | 0.65 | SLC22A12 (0.47) | RARBTP53 | |
| SCHEMBL124286 | 0.65 | HDAC2 (0.41) | SERPINE1GRIN2B | |
| SCHEMBL8570658 | 0.63 | TSHR (0.47) | GSK3BALDH1A1KMT2ATP53 | |
| SCHEMBL8083502 | 0.62 | BCHE (0.49) | BCHEALDH1A1KMT2ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0821685-A1 | INDOLE-3-CARBONYL AND INDOLE-3-SULFONYL DERIVATIVES AS PLATELET ACTIVATING FACTOR ANTAGONISTS | ABBOTT LABORATORIES (US) | 1998-02-04 | — | — | EP | disclosed |