Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | DPP7 | Q9UHL4 | 14/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | DPP8 | Q6V1X1 | 5/20 | 0.42 |
| ▸ | DPP9 | Q86TI2 | 4/20 | 0.42 |
| ▸ | DPP4 | P27487 | 7/20 | 0.40 |
| ▸ | FAP | Q12884 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24322744 | 0.84 | DPP7 (0.68) | ALDH1A1MEN1KMT2ADPP7NPC1 | |
| SCHEMBL24324253 | 0.80 | DPP4 (0.55) | ALDH1A1MEN1KMT2ADPP7DPP8 | |
| SCHEMBL24322510 | 0.80 | DPP4 (0.55) | ALDH1A1MEN1KMT2ADPP7DPP8 | |
| SCHEMBL7318947 | 0.79 | DPP4 (0.50) | ALDH1A1MEN1KMT2ADPP7NPC1 | |
| SCHEMBL14850854 | 0.78 | ALDH1A1 (0.55) | ALDH1A1MEN1KMT2ADPP7NPC1 | |
| SCHEMBL24965915 | 0.76 | ALDH1A1 (0.51) | ALDH1A1MEN1KMT2ADPP7NPC1 | |
| SCHEMBL7330894 | 0.76 | DPP7 (0.44) | DPP7DPP8DPP9DPP4 | |
| SCHEMBL7330876 | 0.76 | DPP7 (0.44) | DPP7DPP8DPP9DPP4 | |
| SCHEMBL13621566 | 0.75 | ALDH1A1 (0.44) | ALDH1A1MEN1KMT2ADPP7NPC1 | |
| SCHEMBL6605447 | 0.74 | F2 (0.39) | ALDH1A1MEN1KMT2ADPP7DPP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996002517-A1 | SUBSTITUTED ARYLSULFONAMIDES, THEIR PREPARATION AND USE AS THROMBIN-INHIBITING MEDICAMENTS | DR. KARL THOMAE GMBH (DE) | 1996-02-01 | — | — | WO | disclosed |