SCHEMBL24322744

SCHEMBL24322744

CC1CCN(C(=O)[C@@H](N)CCCCN)CC1

nearest known ligand 0.68

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
DPP7 Q9UHL4 14/20 0.68
DPP8 Q6V1X1 6/20 0.58
DPP9 Q86TI2 6/20 0.58
DPP4 P27487 6/20 0.56
FAP Q12884 1/20 0.51
ITGB3 P05106 2/20 0.48
ITGA2B P08514 2/20 0.48
MEN1 O00255 1/20 0.47
ALDH1A1 P00352 1/20 0.47
KMT2A Q03164 1/20 0.47
NPC1 O15118 1/20 0.45
GSR P00390 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9054356 0.84 ALDH1A1 (0.51) DPP7DPP8DPP9DPP4FAP
SCHEMBL2694035 0.82 DPP7 (0.64) DPP7DPP8DPP9DPP4FAP
SCHEMBL14850854 0.82 ALDH1A1 (0.55) DPP7DPP8DPP9DPP4MEN1
SCHEMBL29049118 0.82 DPP7 (0.64) DPP7DPP8DPP9DPP4FAP
SCHEMBL6752685 0.80 DPP7 (0.62) DPP7DPP8DPP9DPP4FAP
SCHEMBL15247209 0.80 DPP7 (0.58) DPP7DPP8DPP9DPP4FAP
SCHEMBL24324253 0.80 DPP4 (0.55) DPP7DPP8DPP9DPP4MEN1
SCHEMBL24322510 0.80 DPP4 (0.55) DPP7DPP8DPP9DPP4MEN1
SCHEMBL7318947 0.79 DPP4 (0.50) DPP7DPP8DPP9DPP4FAP
SCHEMBL15247211 0.78 DPP7 (0.56) DPP7DPP8DPP9DPP4FAP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220122691-A1 HtrA Inhibitors and CagA Inhibitors and Use Thereof Psomagen Inc. (US) 2022-04-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220122691-A1 HtrA Inhibitors and CagA Inhibitors and Use Thereof HTRA1, GIPR, HPN DPP7 367/4885DPP8 296/4885DPP9 138/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.