Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 3/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | STAT1 | P42224 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Styrene SCHEMBL134355 | 0.78 | AKR1C3 (0.59) | AKR1C3ALDH1A1TSHRHTTGLA | |
| Styrene SCHEMBL238869 | 0.78 | AKR1C3 (0.59) | AKR1C3ALDH1A1TSHRHTTGLA | |
| Styrene SCHEMBL17687603 | 0.76 | AKR1C3 (0.57) | AKR1C3ALDH1A1TSHRHTTGLA | |
| Styrene SCHEMBL1628243 | 0.76 | AKR1C3 (0.81) | AKR1C3ALDH1A1TSHRHTTMEN1 | |
| Styrene SCHEMBL28361007 | 0.76 | ALDH1A1 (0.58) | AKR1C3ALDH1A1TSHRHTTGLA | |
| Styrene SCHEMBL385100 | 0.75 | ALDH1A1 (0.70) | AKR1C3ALDH1A1TSHRHTTGLA | |
| Styrene SCHEMBL10614939 | 0.75 | ALDH1A1 (0.70) | AKR1C3ALDH1A1TSHRHTTGLA | |
| Styrene SCHEMBL5858997 | 0.75 | ALDH1A1 (0.70) | AKR1C3ALDH1A1TSHRHTTGLA | |
| Styrene SCHEMBL1126458 | 0.75 | AKR1C3 (0.55) | AKR1C3ALDH1A1TSHRHTTGLA | |
| Styrene SCHEMBL93464 | 0.75 | AKR1C3 (0.55) | AKR1C3ALDH1A1TSHRHTTGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0446636-B1 | External application base or auxiliary agent and external application composition for human being or animal containing the same | SHOWA DENKO KK (JP) | 1996-06-12 | — | — | EP | disclosed |
| US-5455042-A | Ointment comprising a homogenous mixture of a polymer or copolymer of N-vinylacetamide, water and/or alcohols, and a pharmacologically active component | SHOWA DENKO KABUSHIKI KAISHA (JP) | 1995-10-03 | — | — | US | disclosed |
| US-5344655-A | Drug delivery | SHOWA DENKO K.K. (JP) | 1994-09-06 | — | — | US | disclosed |
| US-5254338-A | N-vinylacetamide polymer | SHOWA DENKO K.K. (JP) | 1993-10-19 | — | — | US | disclosed |
| EP-0446636-A2 | External application base or auxiliary agent and external application composition for human being or animal containing the same | SHOWA DENKO KABUSHIKI KAISHA (JP) | 1991-09-18 | — | — | EP | disclosed |