Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3527656 | 0.75 | KDM1A (0.36) | SIGMAR1THRB | |
| SCHEMBL2443380 | 0.75 | KDM1A (0.36) | SIGMAR1THRB | |
| SCHEMBL3527654 | 0.73 | ALDH1A1 (0.33) | — | |
| SCHEMBL2445361 | 0.71 | ALDH1A1 (0.33) | — | |
| SCHEMBL16835035 | 0.71 | — | — | |
| SCHEMBL18355180 | 0.71 | — | — | |
| SCHEMBL16835234 | 0.70 | P2RX7 (0.33) | — | |
| SCHEMBL16835233 | 0.70 | P2RX7 (0.33) | — | |
| SCHEMBL2446973 | 0.70 | PTK2 (0.42) | — | |
| SCHEMBL3327660 | 0.69 | TOP2A (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996014296-A1 | NOVEL PYRROLINONE-BASED COMPOUNDS | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 1996-05-17 | — | — | WO | disclosed |
| US-5514814-A | PEPTIDE MIMICS THE INHIBIT PROTEOLYTIC ENZYMES, HIV | TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 1996-05-07 | — | — | US | disclosed |