Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARA | P10276 | 8/20 | 0.37 |
| ▸ | RARB | P10826 | 8/20 | 0.37 |
| ▸ | RARG | P13631 | 8/20 | 0.37 |
| ▸ | RXRA | P19793 | 3/20 | 0.37 |
| ▸ | BACE1 | P56817 | 5/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | APAF1 | O14727 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | CYP26A1 | O43174 | 2/20 | 0.34 |
| ▸ | BACE2 | Q9Y5Z0 | 3/20 | 0.31 |
| ▸ | CYP26B1 | Q9NR63 | 1/20 | 0.31 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.30 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.30 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9054284 | 0.86 | RARA (0.46) | RARARARBRARGRXRABACE1 | |
| Hydrochloric Acid SCHEMBL21750680 | 0.84 | RARA (0.45) | RARARARBRARGRXRABACE1 | |
| SCHEMBL6668874 | 0.80 | EPHX2 (0.39) | RARARARBRARGRXRABACE1 | |
| SCHEMBL4848764 | 0.79 | RARA (0.37) | RARARARBRARGRXRABACE1 | |
| SCHEMBL19259616 | 0.79 | RARA (0.37) | RARARARBRARGRXRABACE1 | |
| SCHEMBL6670538 | 0.76 | RARA (0.37) | RARARARBRARGRXRAKMT2A | |
| SCHEMBL6243526 | 0.76 | HTT (0.46) | RARARARBRARGBACE1KMT2A | |
| SCHEMBL9006909 | 0.75 | RARA (0.39) | RARARARBRARGRXRAKMT2A | |
| SCHEMBL7717570 | 0.75 | RARB (0.46) | RARARARBRARGRXRAKMT2A | |
| SCHEMBL9054107 | 0.74 | RARA (0.36) | RARARARBRARGRXRABACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5498755-A | IMINE COMPOUNDS FOR SKIN DISORDERS AND ANTIINFLAMMATORY AGENTS | ALLERGAN, INC. | 1996-03-12 | — | — | US | disclosed |
| WO-1996006070-A1 | DISUBSTITUTED ARYL AND HETEROARYL IMINES HAVING RETINOID-LIKE BIOLOGICAL ACTIVITY | ALLERGAN (US) | 1996-02-29 | — | — | WO | disclosed |