Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 9/20 | 0.66 |
| ▸ | MTNR1B | P49286 | 7/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.59 |
| ▸ | MEN1 | O00255 | 4/20 | 0.59 |
| ▸ | MAPT | P10636 | 4/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.57 |
| ▸ | MPO | P05164 | 1/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | HTR1A | P08908 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | NQO2 | P16083 | 1/20 | 0.57 |
| ▸ | HTR2B | P41595 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
| ▸ | BLM | P54132 | 1/20 | 0.57 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8806497 | 0.83 | SNCA (0.56) | MTNR1AMTNR1BALDH1A1HPGDRAB9A | |
| SCHEMBL10670286 | 0.82 | MTNR1A (0.71) | MTNR1AMTNR1BKMT2AMEN1MAPT | |
| SCHEMBL3018752 | 0.80 | MTNR1A (0.70) | MTNR1AMTNR1BKMT2AMEN1MAPT | |
| SCHEMBL4889276 | 0.79 | MTNR1A (0.70) | MTNR1AMTNR1BKMT2AMEN1MAPT | |
| SCHEMBL3024961 | 0.79 | KDM4E (0.75) | MTNR1AMTNR1BKMT2AMEN1MAPT | |
| SCHEMBL9208268 | 0.78 | MEN1 (0.66) | MTNR1AMTNR1BKMT2AMEN1MAPT | |
| SCHEMBL9207220 | 0.78 | MEN1 (0.66) | MTNR1AMTNR1BKMT2AMEN1MAPT | |
| SCHEMBL12845365 | 0.77 | HTR2A (0.61) | MTNR1AMTNR1BKMT2AMEN1MAPT | |
| SCHEMBL12782281 | 0.76 | MAPT (0.61) | KMT2AMEN1MAPTKDM4ETDP1 | |
| SCHEMBL5616635 | 0.75 | MTNR1A (0.85) | MTNR1AMTNR1BKMT2AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996004266-A2 | INDOL, INDAZOL, PYRIDOPYRROL AND PYRIDOPYRAZOL DERIVATIVES WITH ANTI-ASTHMATIC, ANTI-ALLERGIC, ANTI-INFLAMMATORY AND IMMUNOMODULATING EFFECTS | ASTA MEDICA AKTIENGESELLSCHAFT (DE) | 1996-02-15 | — | — | WO | disclosed |