Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 9/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.53 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 16/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 14/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 11/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 9/20 | 0.40 |
| ▸ | USP2 | O75604 | 6/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.38 |
| ▸ | HSP90AB1 | P08238 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 4/20 | 0.35 |
| ▸ | CASP1 | P29466 | 3/20 | 0.35 |
| ▸ | CASP7 | P55210 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CLK4 | Q9HAZ1 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16111934 | 0.82 | ALDH1A1 (0.36) | HSD17B10ALDH1A1HPGDKDM4EADRA1A | |
| SCHEMBL6307466 | 0.80 | CYP1A2 (0.38) | HSD17B10ALDH1A1HPGDCYP1A2CYP3A4 | |
| SCHEMBL7066293 | 0.74 | KDM4E (0.66) | HSD17B10ALDH1A1HPGDKDM4EADRA1A | |
| Famciclovir SCHEMBL8190642 | 0.69 | KDM4E (1.00) | HSD17B10ALDH1A1HPGDKDM4EADRA1A | |
| Famciclovir SCHEMBL2949 | 0.69 | KDM4E (1.00) | HSD17B10ALDH1A1HPGDKDM4EADRA1A | |
| Famciclovir SCHEMBL29357294 | 0.69 | KDM4E (1.00) | HSD17B10ALDH1A1HPGDKDM4EADRA1A | |
| Famciclovir SCHEMBL7103048 | 0.68 | KDM4E (0.98) | HSD17B10ALDH1A1HPGDKDM4EADRA1A | |
| Famciclovir SCHEMBL3932051 | 0.68 | KDM4E (0.98) | HSD17B10ALDH1A1HPGDKDM4EADRA1A | |
| Famciclovir SCHEMBL6471652 | 0.68 | KDM4E (0.98) | HSD17B10ALDH1A1HPGDKDM4EADRA1A | |
| Famciclovir SCHEMBL29098544 | 0.68 | KDM4E (0.98) | HSD17B10ALDH1A1HPGDKDM4EADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996006159-A1 | UNIQUE ASSOCIATED KAPOSI'S SARCOMA VIRUS SEQUENCES AND USES THEREOF | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 1996-02-29 | — | — | WO | disclosed |