Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 1/20 | 0.43 |
| ▸ | F2 | P00734 | 6/20 | 0.41 |
| ▸ | AIMP2 | Q13155 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9056447 | 0.91 | PLAU (0.42) | PLAUF2AIMP2MEN1KMT2A | |
| SCHEMBL9055420 | 0.84 | MMP13 (0.36) | PLAUF2MEN1KMT2A | |
| SCHEMBL9055583 | 0.83 | MMP13 (0.36) | F2MEN1KMT2A | |
| SCHEMBL9054638 | 0.83 | F2 (0.51) | F2 | |
| SCHEMBL9054647 | 0.82 | MMP13 (0.34) | PLAUF2 | |
| SCHEMBL9054987 | 0.81 | CCR10 (0.54) | — | |
| SCHEMBL9054991 | 0.81 | CCR10 (0.54) | — | |
| SCHEMBL9056668 | 0.81 | MMP13 (0.34) | F2MEN1KMT2A | |
| SCHEMBL9056437 | 0.75 | F2 (0.46) | F2 | |
| SCHEMBL9054473 | 0.73 | CCR10 (0.68) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996002517-A1 | SUBSTITUTED ARYLSULFONAMIDES, THEIR PREPARATION AND USE AS THROMBIN-INHIBITING MEDICAMENTS | DR. KARL THOMAE GMBH (DE) | 1996-02-01 | — | — | WO | disclosed |