Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | ADAMTS7 | Q9UKP4 | 1/20 | 0.33 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.33 |
| ▸ | CCR10 | P46092 | 4/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.31 |
| ▸ | ITGAV | P06756 | 1/20 | 0.31 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.31 |
| ▸ | F2 | P00734 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9055420 | 0.98 | MMP13 (0.36) | MMP13HTTADAMTS7ADAMTS5CCR10 | |
| SCHEMBL9056668 | 0.92 | MMP13 (0.34) | MMP13ADAMTS7ADAMTS5MEN1ALDH1A1 | |
| SCHEMBL9054647 | 0.89 | MMP13 (0.34) | MMP13HTTADAMTS7ADAMTS5CCR10 | |
| SCHEMBL9054644 | 0.83 | PLAU (0.43) | MEN1KMT2AF2 | |
| SCHEMBL9055077 | 0.77 | F2 (0.37) | F2 | |
| SCHEMBL9055516 | 0.76 | ITGB3 (0.40) | ITGB3ITGAVITGA2BF2 | |
| SCHEMBL9056670 | 0.76 | CCR10 (0.51) | CCR10 | |
| SCHEMBL9056447 | 0.76 | PLAU (0.42) | MEN1ALDH1A1KMT2AF2 | |
| SCHEMBL9055502 | 0.76 | F2 (0.40) | ITGB3ITGAVITGA2BF2 | |
| SCHEMBL9055832 | 0.75 | CCR10 (0.44) | CCR10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996002517-A1 | SUBSTITUTED ARYLSULFONAMIDES, THEIR PREPARATION AND USE AS THROMBIN-INHIBITING MEDICAMENTS | DR. KARL THOMAE GMBH (DE) | 1996-02-01 | — | — | WO | disclosed |