Ether

Ether

SCHEMBL905494

C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.CCCCCCCCc1ccccc1O.CCOCC.OCCO

nearest known ligand 0.48

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BID P55957 3/20 0.48
MCL1 Q07820 3/20 0.48
BCL2L1 Q07817 2/20 0.48
BAK1 Q16611 2/20 0.48
KAT8 Q9H7Z6 2/20 0.48
SAE1 Q9UBE0 2/20 0.48
PPARG P37231 1/20 0.48
PPARA Q07869 1/20 0.48
EP300 Q09472 1/20 0.48
KAT2A Q92830 1/20 0.48
KAT2B Q92831 1/20 0.48
KAT5 Q92993 1/20 0.48
LIPG Q9Y5X9 1/20 0.47
ALOX5 P09917 2/20 0.46
MAPT P10636 2/20 0.46
ALOX15 P16050 2/20 0.46
MEN1 O00255 1/20 0.46
TP53 P04637 1/20 0.46
CYP3A4 P08684 1/20 0.46
TYR P14679 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ether SCHEMBL11316461 1.00 BID (0.48) BIDMCL1BCL2L1BAK1KAT8
Ether SCHEMBL11602995 1.00 BID (0.48) BIDMCL1BCL2L1BAK1KAT8
Ether SCHEMBL6855037 1.00 BID (0.48) BIDMCL1BCL2L1BAK1KAT8
Ether SCHEMBL6254721 1.00 BID (0.48) BIDMCL1BCL2L1BAK1KAT8
Ether SCHEMBL1671202 0.97 BID (0.50) BIDMCL1BCL2L1BAK1KAT8
Ether SCHEMBL6198089 0.97 BID (0.50) BIDMCL1BCL2L1BAK1KAT8
Ether SCHEMBL5472319 0.95 BID (0.49) BIDMCL1BCL2L1BAK1KAT8
Ether SCHEMBL3672989 0.95 LIPG (0.51) BIDMCL1BCL2L1BAK1KAT8
Ether SCHEMBL8933110 0.95 LIPG (0.51) BIDMCL1BCL2L1BAK1KAT8
Cyclopentane SCHEMBL8723159 0.93 BID (0.47) BIDMCL1BCL2L1BAK1KAT8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 183 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6921537-B2 Preparation and uses of los-depleted outer membrane proteins of gram-negative cocci WYETH (US) 2005-07-26 US claimed
EP-1206189-B1 ROTAVIRUS VACCINE FORMULATIONS MERCK & CO INC (US) 2005-06-01 EP claimed
US-6616931-B1 Containing sugar; phosphate; carboxylate; recombinant human serum albumin or a nonionic surfactant MERCK & CO., INC. 2003-09-09 US claimed
EP-1206189-A4 ROTAVIRUS VACCINE FORMULATIONS MERCK & CO INC (US) 2003-03-12 EP claimed
US-20020136741-A1 Preparation and uses of los-depleted outer membrane proteins of gram-negative cocci AMERICAN CYANAMID COMPANY (US) 2002-09-26 US claimed
EP-1206189-A1 ROTAVIRUS VACCINE FORMULATIONS Merck & Co., Inc. (US) 2002-05-22 EP claimed
US-6355253-B1 BACTERICIDAL ANTIBODIES AMERICAN CYANAMID COMPANY 2002-03-12 US claimed
WO-2002011540-A1 ROTAVIRUS VACCINE FORMULATIONS MERCK & CO., INC. (US) 2002-02-14 WO claimed
WO-2001008495-A1 ROTAVIRUS VACCINE FORMULATIONS MERCK & CO., INC. (US) 2001-02-08 WO claimed
US-5521067-A Bone marrow cell adhesion molecules and process for detecting adherence between cell adhesion molecules and cells generally UNIVERSITY OF ROCHESTER (US) 1996-05-28 US claimed
WO-1995014711-A1 CELL ADHESION MOLECULES AND DETECTING ADHERENCE UNIVERSITY OF ROCHESTER (US) 1995-06-01 WO claimed
US-5357636-A Flexible protective medical gloves and methods for their use DRESDNER JR KARL P (US) 1994-10-25 US claimed
US-5335373-A Protective medical gloves and methods for their use DRESDNER JR KARL P (US) 1994-08-09 US claimed
US-20240192707-A1 MICROFLUIDIC SYSTEM THE UNIVERSITY OF CHICAGO 2024-06-13 US disclosed
US-20240160231-A1 MICROFLUIDIC SYSTEM THE UNIVERSITY OF CHICAGO 2024-05-16 US disclosed
US-11853087-B2 Microfluidic system THE UNIVERSITY OF CHICAGO (US) 2023-12-26 US disclosed
WO-1995014711-A1 CELL ADHESION MOLECULES AND DETECTING ADHERENCE UNIVERSITY OF ROCHESTER (US) 1995-06-01 WO disclosed
US-5357636-A Flexible protective medical gloves and methods for their use DRESDNER JR KARL P (US) 1994-10-25 US disclosed
US-5335373-A Protective medical gloves and methods for their use DRESDNER JR KARL P (US) 1994-08-09 US disclosed
EP-0477972-A2 Nucleotide sequences useful as type-specific probes, PCR primers and LCR probes for the amplification and detection of human papilloma virus, and related kits and methods ABBOTT LABORATORIES (US) 1992-04-01 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020136741-A1 Preparation and uses of los-depleted outer membrane proteins of gram-negative cocci DDOST, STT3B, STT3A BID 3129/4885MCL1 895/4885BCL2L1 2450/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.