Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP2A | P11388 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 5/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 4/20 | 0.34 |
| ▸ | MAOB | P27338 | 2/20 | 0.34 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.33 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.33 |
| ▸ | POLL | Q9UGP5 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | DRD1 | P21728 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
| ▸ | STAT3 | P40763 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30639028 | 1.00 | TOP2A (0.37) | TOP2AACHEMAPTMAOAMAOB | |
| SCHEMBL11869538 | 0.85 | MAOA (0.47) | ACHEMAPTMAOAMAOBSTAT3 | |
| SCHEMBL11870449 | 0.82 | ACHE (0.50) | ACHEMAPTPOLLHTR2AHTR2C | |
| SCHEMBL11879623 | 0.78 | ACHE (0.40) | ACHEMAPTPOLL | |
| SCHEMBL11877616 | 0.75 | PRNP (0.33) | HTR2AHTR2CHTR2BDRD2DRD1 | |
| SCHEMBL18213641 | 0.73 | MAOA (0.41) | TOP2AACHEMAPTMAOAMAOB | |
| SCHEMBL12718511 | 0.72 | ACHE (0.44) | TOP2AACHEMAPTCSNK2A2CSNK2A1 | |
| SCHEMBL9055051 | 0.72 | EEF2K (0.43) | — | |
| SCHEMBL1477544 | 0.71 | ACHE (0.34) | ACHECSNK2A2CSNK2A1 | |
| SCHEMBL29457593 | 0.69 | MAOA (0.43) | ACHEMAPTMAOAMAOBCSNK2A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116903454-A | Method for preparing 3,4, 7-trimethyl-1-indanone by one-step conversion of 2, 5-hexanedione | 中国科学院大连化学物理研究所 | 2023-10-20 | — | — | CN | claimed |
| US-3944679-A | Process for imparting a coumarin-like aroma and flavor to tobacco, foods and drinks | THE JAPAN TOBACCO & SALT PUBLIC CORPORATION (JA) | 1976-03-16 | — | — | US | claimed |
| CN-116903454-A | Method for preparing 3,4, 7-trimethyl-1-indanone by one-step conversion of 2, 5-hexanedione | 中国科学院大连化学物理研究所 | 2023-10-20 | — | — | CN | disclosed |
| CN-116903454-A | Method for preparing 3,4, 7-trimethyl-1-indanone by one-step conversion of 2, 5-hexanedione | 中国科学院大连化学物理研究所 | 2023-10-20 | — | — | CN | disclosed |
| CN-116903454-A | Method for preparing 3,4, 7-trimethyl-1-indanone by one-step conversion of 2, 5-hexanedione | 中国科学院大连化学物理研究所 | 2023-10-20 | — | — | CN | disclosed |
| EP-0567953-B1 | Process for the preparation of substituted indanones | HOECHST AG (DE) | 1996-03-13 | — | — | EP | disclosed |
| US-5329049-A | Process for the preparation of substituted indanones | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-07-12 | — | — | US | disclosed |
| EP-0567953-A1 | Process for the preparation of substituted indanones | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-11-03 | — | — | EP | disclosed |
| US-3944679-A | Process for imparting a coumarin-like aroma and flavor to tobacco, foods and drinks | THE JAPAN TOBACCO & SALT PUBLIC CORPORATION (JA) | 1976-03-16 | — | — | US | disclosed |