SCHEMBL9055510

SCHEMBL9055510

CCCCCCCCCCOC(F)(F)C(F)(F)C(F)OS(=O)(=O)C(F)(F)F

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 1/20 0.35
CA2 P00918 11/20 0.34
CA1 P00915 9/20 0.34
CA9 Q16790 8/20 0.34
CA12 O43570 3/20 0.34
CA7 P43166 3/20 0.34
CA14 Q9ULX7 3/20 0.34
CA3 P07451 2/20 0.34
CA4 P22748 2/20 0.34
CA6 P23280 2/20 0.34
CA5A P35218 2/20 0.34
CA5B Q9Y2D0 2/20 0.34
CES2 O00748 1/20 0.34
RECQL P46063 2/20 0.33
GLA P06280 1/20 0.33
HPGD P15428 1/20 0.33
TSHR P16473 1/20 0.33
MAPK1 P28482 1/20 0.33
EPHX2 P34913 1/20 0.33
BLM P54132 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8659019 0.78 EPHX1 (0.34) EPHX1CA2CA1CA9CA12
SCHEMBL7558660 0.74 EPHX1 (0.38) EPHX1CA2CA1CA9CA12
SCHEMBL7559926 0.74 EPHX1 (0.38) EPHX1CA2CA1CA9CA12
SCHEMBL7559650 0.74 EPHX1 (0.38) EPHX1CA2CA1CA9CA12
SCHEMBL3803468 0.73 CES2 (0.36) CES2CES1
SCHEMBL8660304 0.72 CA1 (0.30) CA2CA1
SCHEMBL8768889 0.71 TSHR (0.34) CES2HPGDTSHR
SCHEMBL12649167 0.70 CA1 (0.55) EPHX1CA2CA1CA9CA12
SCHEMBL1744340 0.70 CA1 (0.55) EPHX1CA2CA1CA9CA12
SCHEMBL902041 0.70 CA1 (0.55) EPHX1CA2CA1CA9CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1996015092-A1 LIQUID CRYSTAL COMPOUNDS HAVING PERFLUOROETHER TERMINAL PORTIONS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1996-05-23 WO disclosed
EP-0638112-A1 LIQUID CRYSTAL COMPOUNDS HAVING PERFLUOROETHER TERMINAL PORTIONS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1995-02-15 EP disclosed