SCHEMBL8659019

SCHEMBL8659019

CCCCCCOC(F)(F)C(F)(F)OC(C)OS(=O)(=O)C(F)(F)F

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 1/20 0.34
CA1 P00915 9/20 0.33
CA2 P00918 9/20 0.33
CA9 Q16790 8/20 0.33
CA12 O43570 3/20 0.33
CA7 P43166 3/20 0.33
CA14 Q9ULX7 3/20 0.33
CA3 P07451 2/20 0.33
CA4 P22748 2/20 0.33
CA6 P23280 2/20 0.33
CA5A P35218 2/20 0.33
CA5B Q9Y2D0 2/20 0.33
CES2 O00748 1/20 0.33
RECQL P46063 2/20 0.33
GLA P06280 1/20 0.33
HPGD P15428 1/20 0.33
TSHR P16473 1/20 0.33
MAPK1 P28482 1/20 0.33
EPHX2 P34913 1/20 0.33
BLM P54132 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8660304 0.94 CA1 (0.30) CA1CA2
SCHEMBL8662125 0.79 CA1 (0.31) CA1CA2
SCHEMBL9055510 0.78 EPHX1 (0.35) EPHX1CA1CA2CA9CA12
SCHEMBL9137820 0.76 ADRB2 (0.31)
SCHEMBL9588022 0.74 CES2 (0.35) CES2CES1
SCHEMBL8655675 0.73 CES2 (0.40) EPHX1CES2CES1
SCHEMBL7559650 0.73 EPHX1 (0.38) EPHX1CA1CA2CA9CA12
SCHEMBL7558660 0.73 EPHX1 (0.38) EPHX1CA1CA2CA9CA12
SCHEMBL7559926 0.73 EPHX1 (0.38) EPHX1CA1CA2CA9CA12
SCHEMBL8655745 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0646575-B1 Process for preparing fluorocarbon fluoroalkanesulfonates MINNESOTA MINING & MFG (US) 1998-11-04 EP disclosed
US-5550273-A Process for preparing fluorocarbon fluoroalkanesulfonates MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1996-08-27 US disclosed
EP-0646575-A1 Process for preparing fluorocarbon fluoroalkanesulfonates MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1995-04-05 EP disclosed