Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 3/20 | 0.65 |
| ▸ | ACACA | Q13085 | 1/20 | 0.65 |
| ▸ | ALOX5 | P09917 | 16/20 | 0.61 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9047623 | 0.89 | ACACB (0.55) | ACACBACACAALOX5EPHX2 | |
| SCHEMBL7206818 | 0.89 | ALOX5 (0.64) | ACACBACACAALOX5EPHX2 | |
| SCHEMBL9045275 | 0.86 | ACACB (0.53) | ACACBACACAALOX5EPHX2 | |
| SCHEMBL9049700 | 0.85 | ALOX5 (0.53) | ACACBACACAALOX5EPHX2 | |
| SCHEMBL9048145 | 0.84 | ALOX5 (0.59) | ACACBACACAALOX5EPHX2 | |
| SCHEMBL8304458 | 0.80 | ALOX5 (0.60) | ACACBACACAALOX5EPHX2 | |
| SCHEMBL9046363 | 0.80 | ALOX5 (0.55) | ACACBACACAALOX5EPHX2 | |
| SCHEMBL16705052 | 0.79 | ACACB (1.00) | ACACBACACAALOX5 | |
| SCHEMBL9048203 | 0.79 | ALOX5 (0.79) | ACACBACACAALOX5EPHX2 | |
| SCHEMBL9047913 | 0.77 | ALOX5 (0.59) | ACACBACACAALOX5EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0540673-B1 | ACETYLENE DERIVATIVES HAVING LIPOXYGENASE INHIBITORY ACTIVITY | ABBOTT LAB (US) | 1996-10-16 | — | — | EP | claimed |