SCHEMBL9055545

SCHEMBL9055545

Cc1c(S)cccc1N1CCNCC1

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADRB1 P08588 5/20 0.69
HTR6 P50406 5/20 0.55
HTR7 P34969 2/20 0.51
HTR3A P46098 4/20 0.51
CYP1A2 P05177 3/20 0.51
HTR1A P08908 3/20 0.51
CYP2D6 P10635 3/20 0.51
CYP3A4 P08684 2/20 0.51
CYP2C9 P11712 2/20 0.51
DRD2 P14416 2/20 0.50
DRD3 P35462 2/20 0.50
HTR3E A5X5Y0 2/20 0.50
HTR3B O95264 2/20 0.50
HTR3D Q70Z44 2/20 0.50
HTR3C Q8WXA8 2/20 0.50
SIGMAR1 Q99720 2/20 0.50
NCF1 P14598 1/20 0.50
TSHR P16473 1/20 0.50
NFKB1 P19838 1/20 0.50
HTR1D P28221 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7979300 0.82 ADRB1 (0.74) ADRB1HTR6HTR7HTR3ACYP1A2
SCHEMBL29699369 0.81 ADRB1 (1.00) ADRB1HTR6HTR7HTR3ACYP1A2
SCHEMBL218837 0.81 ADRB1 (1.00) ADRB1HTR6HTR7HTR3ACYP1A2
SCHEMBL10993647 0.81 ADRB1 (0.62) ADRB1HTR6HTR7HTR3ACYP1A2
M-Xylene SCHEMBL27973785 0.80 HTR1A (0.58) ADRB1HTR6HTR7HTR3ACYP1A2
Hydrochloric Acid SCHEMBL1894847 0.80 ADRB1 (0.96) ADRB1HTR6HTR7HTR3ACYP1A2
Piperazine SCHEMBL27593403 0.80 ADRB1 (0.96) ADRB1HTR6HTR7HTR3ACYP1A2
Iodide SCHEMBL11457680 0.80 ADRB1 (0.96) ADRB1HTR6HTR7HTR3ACYP1A2
Hydrochloric Acid SCHEMBL27850954 0.80 ADRB1 (0.96) ADRB1HTR6HTR7HTR3ACYP1A2
Benzene SCHEMBL27973933 0.79 ADRB1 (0.60) ADRB1HTR6HTR7HTR3ACYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140273458-A1 Chemical Mechanical Planarization for Tungsten-Containing Substrates AIR PRODUCTS AND CHEMICALS, INC. (US) 2014-09-18 US claimed
EP-2779217-A2 Chemical mechanical planarization for tungsten-containing substrates AIR PRODUCTS AND CHEMICALS, INC. (US) 2014-09-17 EP claimed
CN-104203928-A Triazinone compound and T-type calcium channel inhibitor NISSAN CHEMICAL IND LTD 2014-12-10 CN disclosed
US-20140273458-A1 Chemical Mechanical Planarization for Tungsten-Containing Substrates AIR PRODUCTS AND CHEMICALS, INC. (US) 2014-09-18 US disclosed
EP-2779217-A2 Chemical mechanical planarization for tungsten-containing substrates AIR PRODUCTS AND CHEMICALS, INC. (US) 2014-09-17 EP disclosed
CN-101835448-B Hair care compositions and methods of treating hair LIVING PROOF INC 2013-03-27 CN disclosed
CN-101835448-A Hair care compositions and methods of treating hair LIVING PROOF INC 2010-09-15 CN disclosed
CN-1680419-A Ketolactones, their use and process for their preparation and pharmaceutical compositions containing them ABBOTT LAB (US) 2005-10-12 CN disclosed
CN-1680420-A Ketolactones, their use and process for their preparation and pharmaceutical compositions containing them ABBOTT LAB (US) 2005-10-12 CN disclosed
CN-1680418-A Ketolactones, their use and process for their preparation and pharmaceutical compositions containing them ABBOTT LAB (US) 2005-10-12 CN disclosed
CN-1214632-A Remedies or preventives for AIDS SANKYO CO (JP) 1999-04-21 CN disclosed
WO-1996002510-A1 NOVEL 1-[4(AMINO METHYL)PHENYL] SUBSTITUTED QUINOLONE CARBOXYLIC ACIDS BAYER AKTIENGESELLSCHAFT (DE) 1996-02-01 WO disclosed
EP-0322643-B1 MEDICINES CONTAINING AS A MIXTURE INTERFERON AND 1-DESOXY-PIPERIDINOSES, PROCESS FOR THEIR MANUFACTURE AND THEIR USE BAYER AG (DE) 1991-07-24 EP disclosed
US-4940705-A VIRICIDES BAYER AKTIENGESELLSCHAFT (DE) 1990-07-10 US disclosed
EP-0322643-A1 Medicines containing as a mixture interferon and 1-desoxy-piperidinoses, process for their manufacture and their use BAYER AG (DE) 1989-07-05 EP disclosed
EP-0313974-A1 N-substituted derivatives of 1-desoxynojirimycine and 1-desoxymannonojirimycine, process for their preparation and their use as pharmaceuticals BAYER AG (DE) 1989-05-03 EP disclosed