Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 4/20 | 0.44 |
| ▸ | GRM3 | Q14832 | 4/20 | 0.44 |
| ▸ | PPARG | P37231 | 2/20 | 0.43 |
| ▸ | PPARA | Q07869 | 2/20 | 0.43 |
| ▸ | LTB4R | Q15722 | 4/20 | 0.42 |
| ▸ | PLAAT3 | P53816 | 2/20 | 0.41 |
| ▸ | PLAAT5 | Q96KN8 | 2/20 | 0.41 |
| ▸ | PLAAT2 | Q9NWW9 | 2/20 | 0.41 |
| ▸ | PLAAT4 | Q9UL19 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | IGF1R | P08069 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 3/20 | 0.39 |
| ▸ | CES1 | P23141 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7614058 | 0.88 | MAPT (0.55) | GRM2GRM3LTB4RMAPTRXFP1 | |
| SCHEMBL7620869 | 0.88 | MAPT (0.55) | GRM2GRM3LTB4RMAPTRXFP1 | |
| SCHEMBL7615234 | 0.88 | MAPT (0.55) | GRM2GRM3LTB4RMAPTRXFP1 | |
| SCHEMBL7620987 | 0.88 | MAPT (0.55) | GRM2GRM3LTB4RMAPTRXFP1 | |
| SCHEMBL7620024 | 0.88 | MAPT (0.55) | GRM2GRM3LTB4RMAPTRXFP1 | |
| SCHEMBL7614749 | 0.88 | MAPT (0.55) | GRM2GRM3LTB4RMAPTRXFP1 | |
| SCHEMBL7614699 | 0.85 | HDAC1 (0.54) | GRM2GRM3MAPT | |
| SCHEMBL9056155 | 0.84 | S1PR2 (0.46) | GRM2GRM3LTB4RMAPTRXFP1 | |
| SCHEMBL22921342 | 0.83 | LTB4R (0.57) | GRM2GRM3PPARGPPARALTB4R | |
| SCHEMBL7619938 | 0.82 | MAPT (0.49) | GRM2GRM3LTB4RMAPTRXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996011901-A1 | NOVEL α,α,α',α'-TETRACHLOROBICARBOXYLIC ACIDS, PROCESS FOR PRODUCING THEM AND MEDICAMENTS CONTAINING THEM | BOEHRINGER MANNHEIM GMBH (DE) | 1996-04-25 | — | — | WO | disclosed |