Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 18/20 | 0.37 |
| ▸ | DDB1 | Q16531 | 17/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | IKZF3 | Q9UKT9 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11880678 | 0.72 | OR51E2 (0.32) | CRBNESR2 | |
| SCHEMBL2974249 | 0.72 | CRBN (0.32) | CRBNDDB1ESR2IKZF3 | |
| SCHEMBL12473611 | 0.72 | CRBN (0.32) | CRBNDDB1 | |
| SCHEMBL9731788 | 0.71 | MAPT (0.34) | CRBNDDB1 | |
| SCHEMBL7098448 | 0.69 | CRBN (0.36) | CRBNDDB1 | |
| SCHEMBL6163559 | 0.69 | ESR2 (0.32) | ESR2 | |
| SCHEMBL33371399 | 0.67 | CRBN (0.33) | CRBNDDB1ALDH1A1CHRM2OPRM1 | |
| SCHEMBL68773 | 0.67 | CRBN (0.33) | CRBNDDB1ALDH1A1CHRM2OPRM1 | |
| SCHEMBL9056440 | 0.66 | DDB1 (0.30) | CRBNDDB1 | |
| SCHEMBL9239478 | 0.66 | CRBN (0.37) | CRBNDDB1IKZF3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996014844-A1 | CYCLIC AMIDINE ANALOGS AS INHIBITORS OF NITRIC OXIDE SYNTHASE | MERCK & CO., INC. (US) | 1996-05-23 | — | — | WO | disclosed |