Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPSE | Q9Y251 | 4/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | TP53 | P04637 | 3/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | METAP1 | P53582 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | METAP2 | P50579 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cambendazole SCHEMBL8734398 | 0.89 | METAP1 (0.57) | HPSESMN1; SMN2TP53TDP1METAP1 | |
| Cambendazole SCHEMBL44000 | 0.84 | METAP1 (0.48) | SMN1; SMN2TP53TDP1METAP1KDM4E | |
| Cambendazole SCHEMBL29409263 | 0.84 | METAP1 (0.48) | SMN1; SMN2TP53TDP1METAP1KDM4E | |
| Cambendazole SCHEMBL2895694 | 0.84 | METAP1 (0.55) | SMN1; SMN2TP53TDP1METAP1KDM4E | |
| Diethenofencarb SCHEMBL9055854 | 0.81 | SMN1; SMN2 (0.61) | HPSESMN1; SMN2TP53NPC1CYP1A2 | |
| Diethenofencarb SCHEMBL29467779 | 0.81 | SMN1; SMN2 (0.61) | HPSESMN1; SMN2TP53NPC1CYP1A2 | |
| Diethenofencarb SCHEMBL22967 | 0.75 | KDM4E (0.56) | SMN1; SMN2TDP1KDM4ENPC1CYP1A2 | |
| Mebendazole SCHEMBL2406875 | 0.74 | METAP1 (0.54) | SMN1; SMN2TP53TDP1METAP1KDM4E | |
| SCHEMBL3500748 | 0.74 | METAP1 (0.52) | HPSESMN1; SMN2TP53TDP1METAP1 | |
| SCHEMBL3500750 | 0.74 | METAP1 (0.59) | SMN1; SMN2TP53TDP1METAP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996015107-A1 | DITHIOCARBAMATE DERIVATIVES | BAYER AKTIENGESELLSCHAFT (DE) | 1996-05-23 | — | — | WO | disclosed |