Cambendazole

Cambendazole

SCHEMBL29409263

CC(C)OC(=O)Nc1ccc2[nH]c(-c3cscn3)nc2c1

nearest known ligand 0.85

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
METAP1 P53582 8/20 0.48
METAP2 P50579 5/20 0.47
KDM4E B2RXH2 3/20 0.47
NPC1 O15118 3/20 0.47
RAB9A P51151 3/20 0.47
SMN1; SMN2 Q16637 3/20 0.47
TP53 P04637 2/20 0.47
CYP1A2 P05177 2/20 0.47
CYP2D6 P10635 2/20 0.47
CYP2C19 P33261 2/20 0.47
CYP3A4 P08684 1/20 0.47
ADORA3 P0DMS8 1/20 0.47
TSHR P16473 1/20 0.47
FKBP1A P62942 1/20 0.47
HIF1A Q16665 1/20 0.47
TDP1 Q9NUW8 1/20 0.47
HDAC6 Q9UBN7 1/20 0.47
CA12 O43570 1/20 0.43
CA1 P00915 1/20 0.43
CA2 P00918 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Cambendazole SCHEMBL44000 1.00 METAP1 (0.48) METAP1METAP2KDM4ENPC1RAB9A
Cambendazole SCHEMBL8734398 0.95 METAP1 (0.57) METAP1METAP2KDM4ENPC1RAB9A
Cambendazole SCHEMBL2895694 0.92 METAP1 (0.55) METAP1METAP2KDM4ENPC1RAB9A
SCHEMBL3500748 0.89 METAP1 (0.52) METAP1METAP2KDM4ENPC1RAB9A
Mebendazole SCHEMBL2406875 0.85 METAP1 (0.54) METAP1METAP2KDM4ENPC1RAB9A
Diethenofencarb SCHEMBL9055860 0.84 HPSE (0.51) METAP1METAP2KDM4ENPC1RAB9A
SCHEMBL11208569 0.83 METAP1 (0.55) METAP1METAP2KDM4ENPC1RAB9A
SCHEMBL5190850 0.82 TUBB4A (0.43) KDM4ENPC1RAB9ASMN1; SMN2TP53
SCHEMBL4367982 0.81 METAP1 (0.50) METAP1METAP2KDM4ENPC1RAB9A
SCHEMBL4366074 0.81 METAP1 (0.50) METAP1METAP2KDM4ENPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250295787-A1 PRESERVED ETHERIFIED CYCLODEXTRIN DERIVATIVES CONTAINING LIQUID AQUEOUS PHARMACEUTICAL COMPOSITION BOEHRINGER INGELHEIM VETMEDICA GMBH (DE) 2025-09-25 US claimed
WO-2024118002-A1 PHOTOBIOREACTOR SYSTEM FOR THE REDUCTION OF AMMONIA AND CARBON DIOXIDE GASES IN POULTRY HOUSES BURSA ULUDAĞ ÜNİVERSİTESİ (TR) 2024-06-06 WO claimed
EP-3021832-B9 PRESERVED ETHERIFIED CYCLODEXTRIN DERIVATIVES CONTAINING LIQUID AQUEOUS PHARMACEUTICAL COMPOSITION BOEHRINGER INGELHEIM VETMEDICA GMBH (DE) 2023-03-15 EP claimed
EP-3599855-B1 DELAYED RELEASE FEED-THROUGH VETERINARY COMPOSITIONS WITH OVICIDAL AND LARVICIDAL ACTIVITY AGAINST SUSCEPTIBLE AND RESISTANT STRAINS OF PARASITES IN RUMINANTS' FECES, USE OF THESE COMPOSITIONS, METHOD FOR DELAYING THE RELEASE OF THESE COMPOSITIONS Champion USA LLC (US) 2022-03-02 EP claimed
US-20250325494-A1 COMPOSITION FOR ORGAN-SPECIFIC DELIVERY OF NUCLEIC ACID THEMEDIUM THERAPEUTICS CO., LTD. (CN) 2025-10-23 US disclosed
US-20250295787-A1 PRESERVED ETHERIFIED CYCLODEXTRIN DERIVATIVES CONTAINING LIQUID AQUEOUS PHARMACEUTICAL COMPOSITION BOEHRINGER INGELHEIM VETMEDICA GMBH (DE) 2025-09-25 US disclosed
US-12357696-B2 Preserved etherified cyclodextrin derivatives containing liquid aqueous pharmaceutical composition BOEHRINGER INGELHEIM VETMEDICA GMBH (DE) 2025-07-15 US disclosed
US-20250188013-A1 LIPID COMPOUND AND USE THEREOF THEMEDIUM THERAPEUTICS CO., LTD. (CN) 2025-06-12 US disclosed
EP-3253757-B1 2-(HET)ARYL-SUBSTITUTED CONDENSED BICYCLIC HETEROCYCLE DERIVATIVES AS PESTICIDES BAYER CROPSCIENCE AG (DE) 2025-03-19 EP disclosed
EP-4393511-A1 LIPID COMPOUND AND USE THEREOF Themedium Therapeutics Co., Ltd. (CN) 2024-07-03 EP disclosed
EP-4393484-A1 COMPOSITION FOR ORGAN-SPECIFIC DELIVERY OF NUCLEIC ACID Themedium Therapeutics Co., Ltd. (CN) 2024-07-03 EP disclosed
WO-2024118002-A1 PHOTOBIOREACTOR SYSTEM FOR THE REDUCTION OF AMMONIA AND CARBON DIOXIDE GASES IN POULTRY HOUSES BURSA ULUDAĞ ÜNİVERSİTESİ (TR) 2024-06-06 WO disclosed
EP-4055010-A1 SUBSTITUTED SULFONYL AMIDES FOR CONTROLLING ANIMAL PESTS Bayer Aktiengesellschaft (DE) 2022-09-14 EP disclosed
EP-4036083-A1 5-OXY SUBSTITUTED HETEROCYCLES AS PESTICIDES Bayer Aktiengesellschaft (DE) 2022-08-03 EP disclosed
EP-4003966-A1 5-AMINO SUBSTITUTED PYRAZOLES AND TRIAZOLES AS PEST CONTROL AGENTS Bayer Aktiengesellschaft (DE) 2022-06-01 EP disclosed
EP-3765466-B1 CONDENSED BICYCLIC HETEROCYCLE DERIVATIVES AS PESTICIDES BAYER AG (DE) 2022-05-25 EP disclosed
EP-3765465-B1 CONDENSED BICYCLIC HETEROCYCLE DERIVATIVES AS PESTICIDES BAYER AG (DE) 2022-05-25 EP disclosed
EP-3615540-B1 CONDENSED BICYCLIC HETEROCYCLE DERIVATIVES AS PESTICIDES BAYER AG (DE) 2022-04-27 EP disclosed
EP-3974414-A1 5-AMINO SUBSTITUTED PYRAZOLES AND TRIAZOLES AS PESTICIDES Bayer AG (DE) 2022-03-30 EP disclosed
WO-2022053453-A1 AZOLE CARBOXAMIDE AS PEST CONTROL AGENTS BAYER AKTIENGESELLSCHAFT (DE) 2022-03-17 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12357696-B2 Preserved etherified cyclodextrin derivatives containing liquid aqueous pharmaceutical composition SI, PIM1, PIM3 METAP1 4691/4885METAP2 4764/4885KDM4E 1216/4885
US-20250295787-A1 PRESERVED ETHERIFIED CYCLODEXTRIN DERIVATIVES CONTAINING LIQUID AQUEOUS PHARMACEUTICAL COMPOSITION SI, PIM1, PIM3 METAP1 4691/4885METAP2 4764/4885KDM4E 1216/4885
US-20250325494-A1 COMPOSITION FOR ORGAN-SPECIFIC DELIVERY OF NUCLEIC ACID FABP1, POLRMT, LIPC METAP1 1925/4885METAP2 1671/4885KDM4E 4795/4885
US-20250188013-A1 LIPID COMPOUND AND USE THEREOF NPC1L1, CYP46A1, PCSK9 METAP1 1461/4885METAP2 1687/4885KDM4E 3530/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.