SCHEMBL9055883

SCHEMBL9055883

CCCC1CCC(c2c(-c3ccccc3)ccc(F)c2F)CC1

nearest known ligand 0.39

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.39
RAB9A P51151 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
CYP2C9 P11712 1/20 0.35
MEN1 O00255 2/20 0.34
MAPK1 P28482 2/20 0.34
KMT2A Q03164 2/20 0.34
ALDH1A1 P00352 2/20 0.34
LMNA P02545 1/20 0.34
MAPT P10636 1/20 0.34
OPRL1 P41146 5/20 0.33
KDM1A O60341 2/20 0.33
GAA P10253 1/20 0.33
TRPV3 Q8NET8 1/20 0.32
HRH3 Q9Y5N1 1/20 0.32
IGF1R P08069 1/20 0.31
HTT P42858 1/20 0.30
NPSR1 Q6W5P4 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29935072 1.00 KDM4E (0.39) KDM4ERAB9AL3MBTL1CYP2C9MEN1
SCHEMBL28969466 0.92 GAA (0.41) KDM4ERAB9AL3MBTL1CYP2C9MEN1
SCHEMBL9061898 0.91 GAA (0.38) KDM4ERAB9AL3MBTL1CYP2C9MEN1
SCHEMBL8931543 0.91 GAA (0.38) KDM4ERAB9AL3MBTL1CYP2C9MEN1
SCHEMBL29934853 0.91 GAA (0.38) KDM4ERAB9AL3MBTL1CYP2C9MEN1
SCHEMBL29934943 0.89 TRPV3 (0.38) ALDH1A1KDM1ATRPV3IGF1R
SCHEMBL9056025 0.89 TRPV3 (0.38) ALDH1A1KDM1ATRPV3IGF1R
SCHEMBL4650916 0.88 KDM4E (0.38) KDM4ERAB9AL3MBTL1CYP2C9MEN1
SCHEMBL4818957 0.85 OPRL1 (0.41) KDM4ERAB9AL3MBTL1CYP2C9MEN1
SCHEMBL9493979 0.83 KDM4E (0.36) KDM4ERAB9AL3MBTL1CYP2C9MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0733692-A1 Liquid crystalline compound, liquid crystal composition containing the same, and display device Chisso Corporation (JP) 1996-09-25 EP disclosed