SCHEMBL4650916

SCHEMBL4650916

CCCC1CCC(c2ccc(-c3ccccc3)c(C3CCC(CCC)CC3)c2F)CC1

nearest known ligand 0.38

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.38
RAB9A P51151 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
CYP2C9 P11712 1/20 0.35
MEN1 O00255 2/20 0.33
MAPK1 P28482 2/20 0.33
KMT2A Q03164 2/20 0.33
ALDH1A1 P00352 1/20 0.33
LMNA P02545 1/20 0.33
MAPT P10636 1/20 0.33
CHRNB2 P17787 1/20 0.33
CHRNA4 P43681 1/20 0.33
OPRL1 P41146 10/20 0.33
GAA P10253 1/20 0.32
PDK2 Q15119 1/20 0.32
PDK4 Q16654 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9166203 0.90 KDM4E (0.36) KDM4ERAB9AL3MBTL1CYP2C9MEN1
SCHEMBL9493979 0.90 KDM4E (0.36) KDM4ERAB9AL3MBTL1CYP2C9MEN1
SCHEMBL9493973 0.90 KDM4E (0.36) KDM4ERAB9AL3MBTL1CYP2C9MEN1
SCHEMBL27878839 0.89 KDM4E (0.37) KDM4ERAB9AL3MBTL1CYP2C9MEN1
SCHEMBL15255890 0.89 KDM4E (0.37) KDM4ERAB9AL3MBTL1CYP2C9MEN1
SCHEMBL29935072 0.88 KDM4E (0.39) KDM4ERAB9AL3MBTL1CYP2C9MEN1
SCHEMBL9055883 0.88 KDM4E (0.39) KDM4ERAB9AL3MBTL1CYP2C9MEN1
SCHEMBL10532005 0.87 GAA (0.35) KDM4ERAB9AL3MBTL1CYP2C9MEN1
SCHEMBL9174206 0.87 GAA (0.35) KDM4ERAB9AL3MBTL1CYP2C9MEN1
SCHEMBL9639406 0.85 CHRNB2 (0.48) KDM4ERAB9AL3MBTL1CYP2C9MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1599562-B9 NEMATIC LIQUID CRYSTAL MIXTURES FOR BISTABLE DISPLAY DEVICES NEMOPTIC (FR) 2008-09-24 EP claimed
EP-1599562-B1 NEMATIC LIQUID CRYSTAL MIXTURES FOR BISTABLE DISPLAY DEVICES NEMOPTIC (FR) 2007-05-16 EP claimed