Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR3 | Q9UBY5 | 8/20 | 0.40 |
| ▸ | LPAR2 | Q9HBW0 | 7/20 | 0.40 |
| ▸ | BTN3A1 | O00481 | 1/20 | 0.39 |
| ▸ | LPAR1 | Q92633 | 5/20 | 0.33 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.33 |
| ▸ | PGD | P52209 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | FNTA | P49354 | 1/20 | 0.30 |
| ▸ | FNTB | P49356 | 1/20 | 0.30 |
| ▸ | TPI1 | P60174 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2140462 | 0.85 | LPAR3 (0.52) | LPAR3LPAR2BTN3A1LPAR1ENPP2 | |
| SCHEMBL4670993 | 0.74 | LPAR3 (0.53) | LPAR3LPAR2LPAR1ENPP2ALDH1A1 | |
| SCHEMBL31579105 | 0.74 | BTN3A1 (0.41) | LPAR3LPAR2BTN3A1ALDH1A1TSHR | |
| SCHEMBL7621893 | 0.73 | LPAR3 (0.56) | LPAR3LPAR2LPAR1ENPP2ALDH1A1 | |
| SCHEMBL735649 | 0.72 | TSHR (0.37) | LPAR3LPAR2BTN3A1ALDH1A1TSHR | |
| SCHEMBL29870530 | 0.71 | LPAR3 (0.59) | LPAR3LPAR2LPAR1ENPP2ALDH1A1 | |
| SCHEMBL29804741 | 0.71 | LPAR3 (0.59) | LPAR3LPAR2LPAR1ENPP2ALDH1A1 | |
| SCHEMBL7621154 | 0.71 | LPAR3 (0.59) | LPAR3LPAR2LPAR1ENPP2ALDH1A1 | |
| SCHEMBL7624680 | 0.71 | LPAR3 (0.59) | LPAR3LPAR2LPAR1ENPP2ALDH1A1 | |
| Maleic Acid SCHEMBL9055441 | 0.71 | LPAR2 (0.36) | LPAR3LPAR2PGDFNTAFNTB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0446636-B1 | External application base or auxiliary agent and external application composition for human being or animal containing the same | SHOWA DENKO KK (JP) | 1996-06-12 | — | — | EP | disclosed |
| US-5455042-A | Ointment comprising a homogenous mixture of a polymer or copolymer of N-vinylacetamide, water and/or alcohols, and a pharmacologically active component | SHOWA DENKO KABUSHIKI KAISHA (JP) | 1995-10-03 | — | — | US | disclosed |
| US-5344655-A | Drug delivery | SHOWA DENKO K.K. (JP) | 1994-09-06 | — | — | US | disclosed |
| US-5254338-A | N-vinylacetamide polymer | SHOWA DENKO K.K. (JP) | 1993-10-19 | — | — | US | disclosed |
| EP-0446636-A2 | External application base or auxiliary agent and external application composition for human being or animal containing the same | SHOWA DENKO KABUSHIKI KAISHA (JP) | 1991-09-18 | — | — | EP | disclosed |