Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA4 | P22748 | 1/20 | 0.34 |
| ▸ | CA5A | P35218 | 1/20 | 0.34 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.34 |
| ▸ | CASP6 | P55212 | 1/20 | 0.34 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.34 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28612186 | 0.86 | NPSR1 (0.42) | NPSR1KMT2AMEN1POLBHTT | |
| SCHEMBL471978 | 0.82 | NPSR1 (0.49) | NPSR1KMT2AMEN1POLBHTT | |
| SCHEMBL10431511 | 0.81 | NPSR1 (0.49) | NPSR1KMT2AMEN1POLBHTT | |
| SCHEMBL9056100 | 0.81 | NPSR1 (0.49) | NPSR1KMT2AMEN1POLBHTT | |
| SCHEMBL31212640 | 0.78 | NPSR1 (0.44) | NPSR1KMT2AMEN1POLBHTT | |
| SCHEMBL2552588 | 0.78 | NPSR1 (0.44) | NPSR1KMT2AMEN1POLBHTT | |
| SCHEMBL28612183 | 0.77 | LMNA (0.41) | NPSR1KMT2AMEN1POLBHTT | |
| SCHEMBL28612188 | 0.76 | CNR2 (0.40) | NPSR1KMT2AMEN1POLBALDH1A1 | |
| Triphenylphosphine Oxide SCHEMBL29014411 | 0.75 | ACHE (0.53) | NPSR1KMT2AMEN1POLBHTT | |
| SCHEMBL4762963 | 0.75 | POLB (0.52) | NPSR1KMT2AMEN1POLBHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113185404-B | 1, 2-biaxial chiral biaryl compound and preparation method and application thereof | 武汉大学 | 2022-08-05 | — | — | CN | disclosed |