Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 6/20 | 0.41 |
| ▸ | F10 | P00742 | 3/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | PLAT | P00750 | 1/20 | 0.39 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.39 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.39 |
| ▸ | CCR10 | P46092 | 1/20 | 0.38 |
| ▸ | PLAU | P00749 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9054483 | 0.80 | F2 (0.44) | F2F10PRSS1LMNAPLAT | |
| SCHEMBL9065342 | 0.77 | CCR10 (0.58) | F2F10CCR10PLAU | |
| SCHEMBL9056601 | 0.77 | SLC16A3 (0.34) | F2 | |
| SCHEMBL9055609 | 0.77 | ITGB3 (0.36) | F2F10PRSS1LMNAPLAT | |
| SCHEMBL7309906 | 0.76 | F2 (0.46) | F2F10CCR10PLAUMAPT | |
| SCHEMBL7309913 | 0.76 | F2 (0.46) | F2F10CCR10PLAUMAPT | |
| SCHEMBL9056442 | 0.76 | CCR10 (0.44) | F2F10CCR10PLAUMAPT | |
| SCHEMBL9054934 | 0.76 | F2 (0.46) | F2F10PRSS1LMNAPLAT | |
| SCHEMBL9055315 | 0.76 | F2 (0.41) | F2F10PRSS1LMNAPLAT | |
| SCHEMBL9055310 | 0.76 | F2 (0.40) | F2F10PRSS1LMNAPLAT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996002517-A1 | SUBSTITUTED ARYLSULFONAMIDES, THEIR PREPARATION AND USE AS THROMBIN-INHIBITING MEDICAMENTS | DR. KARL THOMAE GMBH (DE) | 1996-02-01 | — | — | WO | disclosed |