Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC16A3 | O15427 | 1/20 | 0.34 |
| ▸ | SLC40A1 | Q9NP59 | 6/20 | 0.33 |
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | PDE2A | O00408 | 1/20 | 0.32 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.32 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.32 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.32 |
| ▸ | F2 | P00734 | 1/20 | 0.31 |
| ▸ | PKLR | P30613 | 1/20 | 0.31 |
| ▸ | PARP1 | P09874 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9056228 | 0.84 | ITGB3 (0.41) | ALDH1A1PDE2APDE3BPDE3AP2RY12 | |
| SCHEMBL9055326 | 0.84 | ITGB3 (0.40) | ALDH1A1PDE2APDE3BPDE3AP2RY12 | |
| SCHEMBL9056960 | 0.83 | ITGB3 (0.40) | PDE2APDE3BPDE3AP2RY12F2 | |
| SCHEMBL8716492 | 0.83 | SLC16A3 (0.37) | SLC16A3SLC40A1HTR6ALDH1A1F2 | |
| SCHEMBL7324729 | 0.81 | HTR6 (0.36) | SLC16A3SLC40A1HTR6ALDH1A1F2 | |
| SCHEMBL9054354 | 0.80 | CCR10 (0.40) | — | |
| SCHEMBL9055303 | 0.78 | ITGB3 (0.44) | SLC16A3 | |
| SCHEMBL9056174 | 0.77 | F2 (0.41) | F2 | |
| SCHEMBL9054627 | 0.77 | CCR10 (0.39) | PDE2APDE3BPDE3AP2RY12 | |
| SCHEMBL9056911 | 0.75 | ITGB3 (0.41) | SLC16A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996002517-A1 | SUBSTITUTED ARYLSULFONAMIDES, THEIR PREPARATION AND USE AS THROMBIN-INHIBITING MEDICAMENTS | DR. KARL THOMAE GMBH (DE) | 1996-02-01 | — | — | WO | disclosed |