Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | HTR7 | P34969 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 2/20 | 0.36 |
| ▸ | DRD4 | P21917 | 2/20 | 0.36 |
| ▸ | DRD3 | P35462 | 2/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA4 | P22748 | 1/20 | 0.34 |
| ▸ | CA6 | P23280 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 3/20 | 0.33 |
| ▸ | ACHE | P22303 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6674901 | 0.83 | PNMT (0.49) | PNMTNPC1RAB9AHTR7HTR2B | |
| SCHEMBL9056261 | 0.83 | PNMT (0.49) | PNMTNPC1RAB9AHTR7HTR2B | |
| SCHEMBL6675789 | 0.80 | PNMT (0.46) | PNMTNPC1RAB9AHTR7HTR2B | |
| SCHEMBL6676496 | 0.78 | PNMT (0.44) | PNMTNPC1RAB9AHTR7HTR2B | |
| SCHEMBL3157927 | 0.77 | PNMT (0.46) | PNMTNPC1RAB9AHTR7HTR2B | |
| SCHEMBL6675580 | 0.77 | PNMT (0.49) | PNMTNPC1RAB9AHTR7HTR2B | |
| SCHEMBL6672847 | 0.77 | PNMT (0.49) | PNMTNPC1RAB9AHTR7HTR2B | |
| SCHEMBL7606251 | 0.77 | PNMT (0.49) | PNMTNPC1RAB9AHTR7HTR2B | |
| SCHEMBL10516045 | 0.77 | PNMT (0.49) | PNMTNPC1RAB9AHTR7HTR2B | |
| SCHEMBL29617348 | 0.77 | PNMT (0.49) | PNMTNPC1RAB9AHTR7HTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996013531-A1 | PREPARATION OF MODIFIED POLYOLEFIN CATALYSTS AND IN SITU PREPARATION OF SUPPORTED METALLOCENE AND ZIEGLER-NATTA/METALLOCENE POLYOLEFIN CATALYSTS | W.R. GRACE & CO.-CONN. (US) | 1996-05-09 | — | — | WO | claimed |
| WO-1996013531-A1 | PREPARATION OF MODIFIED POLYOLEFIN CATALYSTS AND IN SITU PREPARATION OF SUPPORTED METALLOCENE AND ZIEGLER-NATTA/METALLOCENE POLYOLEFIN CATALYSTS | W.R. GRACE & CO.-CONN. (US) | 1996-05-09 | — | — | WO | disclosed |