Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RPA1 | P27694 | 5/20 | 0.90 |
| ▸ | MARS1 | P56192 | 1/20 | 0.74 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.68 |
| ▸ | MDM2 | Q00987 | 7/20 | 0.67 |
| ▸ | MCL1 | Q07820 | 6/20 | 0.67 |
| ▸ | BCL2 | P10415 | 5/20 | 0.67 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.66 |
| ▸ | PPP1CA | P62136 | 1/20 | 0.64 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3139245 | 0.94 | RPA1 (1.00) | RPA1MARS1SMN1; SMN2MDM2MCL1 | |
| SCHEMBL7463244 | 0.91 | RPA1 (0.76) | RPA1MARS1SMN1; SMN2MDM2MCL1 | |
| SCHEMBL9210332 | 0.90 | RPA1 (0.74) | RPA1MARS1SMN1; SMN2MDM2MCL1 | |
| SCHEMBL14504732 | 0.90 | RPA1 (0.74) | RPA1MARS1SMN1; SMN2MDM2MCL1 | |
| SCHEMBL32690380 | 0.90 | RPA1 (0.74) | RPA1MARS1SMN1; SMN2MDM2MCL1 | |
| SCHEMBL27333015 | 0.89 | RPA1 (0.72) | RPA1MARS1SMN1; SMN2MDM2MCL1 | |
| SCHEMBL14504738 | 0.89 | RPA1 (0.72) | RPA1MARS1SMN1; SMN2MDM2MCL1 | |
| SCHEMBL27554183 | 0.89 | CHRNA7 (0.78) | RPA1MARS1SMN1; SMN2CHRNA7 | |
| SCHEMBL14574216 | 0.88 | RPA1 (0.71) | RPA1MARS1SMN1; SMN2MDM2MCL1 | |
| SCHEMBL2911521 | 0.88 | RPA1 (0.70) | RPA1MARS1SMN1; SMN2MDM2MCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996014302-A1 | PYRAZOLE DERIVATIVES EXHIBITING ANTI-INFLAMMATORY AND ANALGESIC EFFECTS | EISAI CO., LTD. (JP) | 1996-05-17 | — | — | WO | disclosed |