Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 2/20 | 0.78 |
| ▸ | RPA1 | P27694 | 2/20 | 0.72 |
| ▸ | PTGS2 | P35354 | 10/20 | 0.70 |
| ▸ | CA1 | P00915 | 1/20 | 0.69 |
| ▸ | CA2 | P00918 | 1/20 | 0.69 |
| ▸ | CA9 | Q16790 | 1/20 | 0.69 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.65 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.65 |
| ▸ | MARS1 | P56192 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6351220 | 0.91 | CHRNA7 (0.78) | CHRNA7PTGS2CA1CA2CA9 | |
| SCHEMBL6342040 | 0.90 | PTGS2 (0.80) | CHRNA7PTGS2CA1CA2CA9 | |
| SCHEMBL9210332 | 0.90 | RPA1 (0.74) | CHRNA7RPA1PTGS2CA1CA2 | |
| SCHEMBL9056282 | 0.89 | RPA1 (0.90) | CHRNA7RPA1SMN1; SMN2MARS1 | |
| SCHEMBL5430032 | 0.87 | CA9 (0.74) | CHRNA7RPA1PTGS2CA1CA2 | |
| SCHEMBL27485652 | 0.86 | PTGS2 (0.65) | CHRNA7RPA1PTGS2CA9PTGS1 | |
| SCHEMBL5236666 | 0.86 | RPA1 (0.72) | RPA1PTGS2CA1CA2CA9 | |
| SCHEMBL3873219 | 0.85 | CHRNA7 (0.80) | CHRNA7RPA1PTGS2SMN1; SMN2MAPK9 | |
| SCHEMBL27485627 | 0.85 | PTGS2 (0.69) | CHRNA7RPA1PTGS2CA1CA2 | |
| SCHEMBL5698710 | 0.85 | PTGS2 (0.76) | CHRNA7PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1202828-A | Substituted pyrzolyl benzenesulfonanides for use in veterinary | SEARLE & CO (US) | 1998-12-23 | — | — | CN | disclosed |