Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | TOP1 | P11387 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | RORC | P51449 | 2/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5529029 | 0.90 | PIM1 (0.47) | PIM1ALDH1A1KDM4EPOLBHSP90AA1 | |
| SCHEMBL9056323 | 0.88 | PIM1 (0.37) | PIM1ALDH1A1KDM4EPOLBHSP90AA1 | |
| SCHEMBL5919530 | 0.85 | PIM1 (0.47) | PIM1ALDH1A1KDM4EPOLBHSP90AA1 | |
| SCHEMBL5919638 | 0.85 | LMNA (0.49) | PIM1ALDH1A1KDM4EPOLBHSP90AA1 | |
| SCHEMBL9055056 | 0.84 | ALDH1A1 (0.44) | PIM1ALDH1A1KDM4EPOLBHSP90AA1 | |
| SCHEMBL9048080 | 0.84 | ALDH1A1 (0.55) | PIM1ALDH1A1KDM4EPOLBHSP90AA1 | |
| SCHEMBL9055161 | 0.83 | LMNA (0.53) | PIM1ALDH1A1KDM4EPOLBHSP90AA1 | |
| SCHEMBL5919385 | 0.82 | HPGD (0.44) | PIM1ALDH1A1KDM4EPOLBHSP90AA1 | |
| SCHEMBL8801305 | 0.82 | PIM1 (0.48) | PIM1ALDH1A1KDM4EPOLBHSP90AA1 | |
| SCHEMBL9056315 | 0.82 | CSF1R (0.42) | PIM1ALDH1A1KDM4EPOLBHSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996002510-A1 | NOVEL 1-[4(AMINO METHYL)PHENYL] SUBSTITUTED QUINOLONE CARBOXYLIC ACIDS | BAYER AKTIENGESELLSCHAFT (DE) | 1996-02-01 | — | — | WO | disclosed |