SCHEMBL9056318

SCHEMBL9056318

O=C(O)c1cc2c(c([N+](=O)[O-])c1)OC(c1ccccc1)(c1ccccc1)O2

nearest known ligand 0.44

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CASP6 P55212 1/20 0.44
MEN1 O00255 1/20 0.43
KMT2A Q03164 1/20 0.43
HCAR3 P49019 4/20 0.42
TSHR P16473 2/20 0.41
LMNA P02545 1/20 0.41
CNR1 P21554 2/20 0.41
POLB P06746 1/20 0.39
ALDH1A1 P00352 2/20 0.38
VCAM1 P19320 1/20 0.38
TPMT P51580 1/20 0.38
CES2 O00748 1/20 0.38
CES1 P23141 1/20 0.38
AR P10275 1/20 0.38
AKR1C4 P17516 1/20 0.38
AKR1C3 P42330 1/20 0.38
AKR1C2 P52895 1/20 0.38
AKR1C1 Q04828 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9062916 0.80 KMT2A (0.43) MEN1KMT2ALMNAPOLBALDH1A1
SCHEMBL4460328 0.79 CNR1 (0.45) MEN1KMT2ATSHRLMNACNR1
SCHEMBL9057465 0.79 XDH (0.39) MEN1KMT2ALMNACNR1ALDH1A1
SCHEMBL9056672 0.77 TSHR (0.33) MEN1KMT2ATSHRLMNACNR1
SCHEMBL7814338 0.75 CA12 (0.44) TSHRLMNACNR1ALDH1A1TPMT
SCHEMBL8728950 0.72 CNR1 (0.63) CNR1ALDH1A1
SCHEMBL9040996 0.71 CNR1 (0.62) CNR1ALDH1A1
SCHEMBL9057677 0.71 MEN1 (0.48) MEN1KMT2A
SCHEMBL9063411 0.70 KMT2A (0.39) MEN1KMT2ATSHRCNR1ALDH1A1
SCHEMBL23630719 0.69 POLB (0.47) MEN1KMT2ATSHRCNR1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1996008483-A1 GALLIC ACID DERIVATIVES, METHOD FOR THEIR PREPARATION AND THEIR USE AS DRUGS ROUSSEL UCLAF (FR) 1996-03-21 WO disclosed