SCHEMBL9057465

SCHEMBL9057465

O=Cc1cc2c(c([N+](=O)[O-])c1)OC(c1ccccc1)(c1ccccc1)O2

nearest known ligand 0.39

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
XDH P47989 1/20 0.39
ALDH5A1 P51649 1/20 0.39
ABAT P80404 1/20 0.39
VCAM1 P19320 1/20 0.39
MAPT P10636 9/20 0.37
ALDH1A1 P00352 7/20 0.37
MEN1 O00255 4/20 0.37
KMT2A Q03164 4/20 0.37
HPGD P15428 4/20 0.37
HTT P42858 3/20 0.37
ALDH3A1 P30838 2/20 0.35
ALDH1A3 P47895 1/20 0.35
NPSR1 Q6W5P4 2/20 0.34
KDM4E B2RXH2 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
CNR1 P21554 2/20 0.33
LMNA P02545 2/20 0.32
SMN1; SMN2 Q16637 2/20 0.32
DBH P09172 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9056318 0.79 CASP6 (0.44) VCAM1ALDH1A1MEN1KMT2ACNR1
SCHEMBL17323185 0.76 CYP1A2 (0.49) XDHALDH5A1ABATVCAM1MAPT
SCHEMBL13890450 0.75 TTR (0.43) ALDH5A1ABATMAPTALDH1A1KMT2A
SCHEMBL9140371 0.72 CNR1 (0.46) ALDH1A1MEN1KMT2AKDM4ECNR1
SCHEMBL17311197 0.71 SIRT1 (0.44) XDHALDH5A1ABATVCAM1MAPT
SCHEMBL17348519 0.68 XDH (0.47) XDHALDH5A1ABATVCAM1MAPT
SCHEMBL1515807 0.67 MAPT (0.46) XDHALDH5A1ABATVCAM1MAPT
SCHEMBL4625398 0.67 TXNRD1 (0.51) XDHALDH5A1ABATVCAM1MAPT
SCHEMBL9670506 0.66 TDP1 (0.62) XDHALDH5A1ABATVCAM1MAPT
SCHEMBL6991121 0.65 LMNA (0.39) ALDH1A1MEN1KMT2AKDM4ECNR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1996008483-A1 GALLIC ACID DERIVATIVES, METHOD FOR THEIR PREPARATION AND THEIR USE AS DRUGS ROUSSEL UCLAF (FR) 1996-03-21 WO disclosed