Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | PGR | P06401 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17019762 | 0.78 | CA1 (0.32) | MAPTBRD4PKMOPRM1HSP90AA1 | |
| SCHEMBL6256987 | 0.76 | PGR (0.44) | KDM4EALDH1A1HPGDPGRBRD4 | |
| SCHEMBL6262202 | 0.75 | PGR (0.46) | KDM4EALDH1A1PGRCA1CA2 | |
| SCHEMBL17019678 | 0.75 | SMN1; SMN2 (0.36) | KDM4EALDH1A1BRD4HTTCA1 | |
| SCHEMBL17019572 | 0.75 | PDE7A (0.33) | BRD4CA1CA2CA7CA9 | |
| SCHEMBL17019570 | 0.73 | BRD4 (0.32) | BRD4 | |
| SCHEMBL18870236 | 0.73 | PDE7A (0.38) | KDM4EALDH1A1MAPTHTTGAA | |
| SCHEMBL17019703 | 0.71 | MAPT (0.33) | MAPT | |
| SCHEMBL17019675 | 0.70 | CYP1A2 (0.40) | OPRM1HTR2AHTR2CHTR2B | |
| SCHEMBL16449706 | 0.67 | MEN1 (0.31) | MEN1ALPLMAPK1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4572796-A | 1,1,4,7-Tetramethyl-3-indanone, product produced thereby and organoleptic uses thereof | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1986-02-25 | — | — | US | claimed |
| EP-0567953-B1 | Process for the preparation of substituted indanones | HOECHST AG (DE) | 1996-03-13 | — | — | EP | disclosed |
| US-5329049-A | Process for the preparation of substituted indanones | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-07-12 | — | — | US | disclosed |
| EP-0567953-A1 | Process for the preparation of substituted indanones | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-11-03 | — | — | EP | disclosed |
| US-4572796-A | 1,1,4,7-Tetramethyl-3-indanone, product produced thereby and organoleptic uses thereof | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1986-02-25 | — | — | US | disclosed |
| US-4572796-A | 1,1,4,7-Tetramethyl-3-indanone, product produced thereby and organoleptic uses thereof | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1986-02-25 | — | — | US | disclosed |
| US-4572796-A | 1,1,4,7-Tetramethyl-3-indanone, product produced thereby and organoleptic uses thereof | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1986-02-25 | — | — | US | disclosed |