SCHEMBL6262202

SCHEMBL6262202

Cc1cccc2c1C(C)(C)CC2=O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PGR P06401 4/20 0.46
DAO P14920 1/20 0.41
ALDH1A1 P00352 2/20 0.41
CA1 P00915 1/20 0.40
CA2 P00918 1/20 0.40
CA7 P43166 1/20 0.40
CA9 Q16790 1/20 0.40
ACHE P22303 1/20 0.39
PARP1 P09874 1/20 0.38
PARP10 Q53GL7 1/20 0.38
PARP11 Q9NR21 1/20 0.38
MEN1 O00255 3/20 0.38
KMT2A Q03164 3/20 0.38
KDM4E B2RXH2 2/20 0.38
POLB P06746 2/20 0.38
PRNP P04156 1/20 0.37
PPARG P37231 1/20 0.37
RXFP1 Q9HBX9 1/20 0.37
NCOR2 Q9Y618 1/20 0.37
CYP2C19 P33261 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17427491 0.81 DAO (0.42) PGRDAOALDH1A1CA1CA2
SCHEMBL9056337 0.76 PGR (0.44) PGRALDH1A1MEN1KMT2AKDM4E
SCHEMBL9056340 0.75 KDM4E (0.36) PGRALDH1A1CA1CA2CA7
SCHEMBL18179342 0.73 PGR (0.39) PGRDAOCA1CA2CA7
SCHEMBL29581434 0.72 PGR (0.51) PGRMEN1KMT2APOLB
SCHEMBL28680129 0.72 POLB (0.54) PGRALDH1A1CA1CA2CA7
SCHEMBL182096 0.72 PGR (0.51) PGRMEN1KMT2APOLB
SCHEMBL6256987 0.72 PGR (0.44) PGRALDH1A1CA1CA2CA7
SCHEMBL12261408 0.72 ALDH1A1 (0.50) PGRDAOALDH1A1CA1CA2
SCHEMBL29060297 0.71 PGR (0.40) PGRALDH1A1MEN1KMT2APOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1310240-B1 6-Alkylindane-1-ones as perfuming agents BELL FLAVORS & FRAGANCES GMBH (DE) 2005-10-19 EP disclosed
EP-1310240-A1 6-Alkylindane-1-ones as perfuming agents HAARMANN & REIMER GMBH (DE) 2003-05-14 EP disclosed