Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | MC4R | P32245 | 1/20 | 0.43 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.43 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.43 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.43 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.43 |
| ▸ | CKS1B | P61024 | 1/20 | 0.43 |
| ▸ | SKP1 | P63208 | 1/20 | 0.43 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | STS | P08842 | 2/20 | 0.42 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9056581 | 1.00 | NAMPT (0.44) | NAMPTACHEMC4RGPR119SMARCA2 | |
| SCHEMBL18878434 | 0.83 | GPR119 (0.50) | NAMPTACHEMC4RGPR119SMARCA2 | |
| SCHEMBL9057950 | 0.82 | GPR119 (0.49) | NAMPTACHEMC4RGPR119SMARCA2 | |
| SCHEMBL8567337 | 0.82 | GPR119 (0.49) | NAMPTACHEMC4RGPR119SMARCA2 | |
| SCHEMBL8561483 | 0.81 | SMARCA2 (0.50) | NAMPTACHEMC4RGPR119SMARCA2 | |
| SCHEMBL8561486 | 0.81 | SMARCA2 (0.50) | NAMPTACHEMC4RGPR119SMARCA2 | |
| SCHEMBL22605981 | 0.81 | GPR119 (0.48) | NAMPTACHEMC4RGPR119SMARCA2 | |
| SCHEMBL5374555 | 0.80 | L3MBTL1 (0.47) | ACHEGPR119CKS1BSKP1SKP2 | |
| SCHEMBL14570987 | 0.80 | L3MBTL1 (0.47) | ACHEGPR119CKS1BSKP1SKP2 | |
| SCHEMBL4513123 | 0.79 | NPY5R (0.48) | NAMPTGPR119SMARCA2SMARCA4PBRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996010568-A1 | SUBSTITUTED ARYL PIPERAZINES AS NEUROKININ ANTAGONISTS | MERCK & CO., INC. (US) | 1996-04-11 | — | — | WO | disclosed |