Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 5/20 | 0.56 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.56 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.46 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.43 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.43 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7942846 | 0.87 | ESR1 (0.51) | ESR1ESR2MAPTKDM4EKMT2A | |
| SCHEMBL7945783 | 0.87 | ESR2 (0.50) | ESR1ESR2MAPTKDM4EKMT2A | |
| SCHEMBL11182261 | 0.87 | ESR1 (0.54) | ESR1ESR2CYP19A1 | |
| SCHEMBL11178289 | 0.86 | ESR1 (0.50) | ESR1ESR2HCRTR1HCRTR2MAPT | |
| SCHEMBL9054865 | 0.86 | ESR1 (0.60) | ESR1ESR2HCRTR1HCRTR2MAPT | |
| SCHEMBL11176566 | 0.84 | ESR1 (0.69) | ESR1ESR2KDM4E | |
| SCHEMBL7945769 | 0.83 | ESR1 (0.53) | ESR1ESR2MAPTKDM4EKMT2A | |
| SCHEMBL4651846 | 0.83 | ESR1 (0.81) | ESR1ESR2MAPTKMT2AMEN1 | |
| SCHEMBL7942835 | 0.82 | ALDH1A1 (0.46) | ESR1ESR2MAPTKDM4EKMT2A | |
| SCHEMBL11179589 | 0.82 | ESR1 (0.83) | ESR1ESR2MAPTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996012489-A1 | BICYCLIC NEUROPEPTIDE Y RECEPTOR ANTAGONISTS | ELI LILLY AND COMPANY (US) | 1996-05-02 | — | — | WO | disclosed |