Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.68 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.68 |
| ▸ | NPC1 | O15118 | 3/20 | 0.68 |
| ▸ | RAB9A | P51151 | 3/20 | 0.68 |
| ▸ | HTT | P42858 | 3/20 | 0.68 |
| ▸ | LMNA | P02545 | 3/20 | 0.68 |
| ▸ | GAA | P10253 | 2/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.68 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.59 |
| ▸ | IDO1 | P14902 | 1/20 | 0.59 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.59 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.57 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.57 |
| ▸ | BRD4 | O60885 | 3/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31442525 | 1.00 | KDM4E (0.68) | KDM4EL3MBTL1NPC1RAB9AHTT | |
| SCHEMBL4538975 | 0.87 | KDM4E (0.68) | KDM4EL3MBTL1NPC1RAB9AHTT | |
| SCHEMBL31106423 | 0.84 | KDM4E (0.68) | KDM4EL3MBTL1NPC1RAB9AHTT | |
| SCHEMBL6892279 | 0.84 | KDM4E (0.68) | KDM4EL3MBTL1NPC1RAB9AHTT | |
| SCHEMBL114710 | 0.81 | KDM4E (0.74) | KDM4EL3MBTL1NPC1RAB9AHTT | |
| SCHEMBL1772089 | 0.81 | KDM4E (0.64) | KDM4EL3MBTL1NPC1RAB9AHTT | |
| SCHEMBL31237495 | 0.81 | KDM4E (0.79) | KDM4EL3MBTL1NPC1RAB9AHTT | |
| SCHEMBL9177673 | 0.81 | KDM4E (0.79) | KDM4EL3MBTL1NPC1RAB9AHTT | |
| SCHEMBL1782934 | 0.81 | KDM4E (1.00) | KDM4EL3MBTL1NPC1RAB9AHTT | |
| SCHEMBL30159468 | 0.81 | KDM4E (1.00) | KDM4EL3MBTL1NPC1RAB9AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996015107-A1 | DITHIOCARBAMATE DERIVATIVES | BAYER AKTIENGESELLSCHAFT (DE) | 1996-05-23 | — | — | WO | disclosed |