SCHEMBL6892279

SCHEMBL6892279

C=CCc1ccc(O)c2ncccc12

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 11/20 0.68
L3MBTL1 Q9Y468 6/20 0.68
LMNA P02545 4/20 0.68
HTT P42858 3/20 0.68
NPC1 O15118 3/20 0.68
RAB9A P51151 2/20 0.68
GAA P10253 2/20 0.68
SMN1; SMN2 Q16637 1/20 0.68
ALOX12 P18054 3/20 0.59
PAX8 Q06710 1/20 0.59
NPSR1 Q6W5P4 1/20 0.59
BRD4 O60885 5/20 0.55
MAPT P10636 3/20 0.55
ALDH1A1 P00352 2/20 0.55
TP53 P04637 2/20 0.55
ALOX15 P16050 2/20 0.55
TDP1 Q9NUW8 2/20 0.55
NFKB1 P19838 1/20 0.55
NFKB2 Q00653 1/20 0.55
RELA Q04206 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31106423 1.00 KDM4E (0.68) KDM4EL3MBTL1LMNAHTTNPC1
SCHEMBL6896595 0.87 KDM4E (0.68) KDM4EL3MBTL1LMNAHTTNPC1
SCHEMBL9280481 0.86 KDM4E (0.47) KDM4EL3MBTL1LMNAHTTNPC1
SCHEMBL31442525 0.84 KDM4E (0.68) KDM4EL3MBTL1LMNAHTTNPC1
SCHEMBL9056804 0.84 KDM4E (0.68) KDM4EL3MBTL1LMNAHTTNPC1
SCHEMBL2523380 0.82 KDM4E (0.60) KDM4EL3MBTL1LMNAHTTNPC1
SCHEMBL1772089 0.81 KDM4E (0.64) KDM4EL3MBTL1LMNAHTTNPC1
SCHEMBL30159468 0.81 KDM4E (1.00) KDM4EL3MBTL1LMNAHTTNPC1
SCHEMBL9177673 0.81 KDM4E (0.79) KDM4EL3MBTL1LMNAHTTNPC1
SCHEMBL1782934 0.81 KDM4E (1.00) KDM4EL3MBTL1LMNAHTTNPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9499739-B2 Thermoplastic resin composition, production method of thermoplastic resin composition, molding material, and light-emitting body Mutsubishi Rayon Co., Ltd. (JP) 2016-11-22 US claimed
US-9499739-B2 Thermoplastic resin composition, production method of thermoplastic resin composition, molding material, and light-emitting body Mutsubishi Rayon Co., Ltd. (JP) 2016-11-22 US disclosed
US-20150299564-A1 THERMOPLASTIC RESIN COMPOSITION, PRODUCTION METHOD OF THERMOPLASTIC RESIN COMPOSITION, MOLDING MATERIAL, AND LIGHT-EMITTING BODY MITSUBISHI RAYON CO., LTD. (JP) 2015-10-22 US disclosed
US-9090820-B2 Thermoplastic resin composition, production method of thermoplastic resin composition, molding material, and light-emitting body MITSUBISHI RAYON CO., LTD. (JP) 2015-07-28 US disclosed
US-20130248765-A1 THERMOPLASTIC RESIN COMPOSITION, PRODUCTION METHOD OF THERMOPLASTIC RESIN COMPOSITION, MOLDING MATERIAL, AND LIGHT-EMITTING BODY MITSUBISHI RAYON CO., LTD. (JP) 2013-09-26 US disclosed
US-20040002578-A1 AIRq'2-type aluminum compound and method for manufacturing the same and derivative thereof TOKYO INSTITUTE OF TECHNOLOGY (JP) 2004-01-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040002578-A1 AIRq'2-type aluminum compound and method for manufacturing the same and derivative thereof RECQL, ATXN2L, KCNQ2 KDM4E 2028/4885L3MBTL1 3007/4885LMNA 4449/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.